Investigating the effect of vitamin D vaginal suppository on sexual function among postmenopausal women: study protocol for a randomized controlled trial

• Published in: BMC women's health Vol. 20; no. 1; pp. 27 - 8
• Main Authors: Sarebani, Zinat, Alimoradi, Zainab, Aali, Ehsan, Mirzadeh, Monirsadat, Chegini, Venus, Abbaspour, Mohammadreza, Griffiths, Mark D.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 18.02.2020; BioMed Central; BMC
• Subjects: Administration, Intravaginal; Aged; Analysis; Atrophy; Cardiovascular disease; Clinical trials; Diabetes; Dietary supplements; Estrogens; Female; Hormone replacement therapy; Humans; Information management; Menopause; Metabolism; Middle Aged; Osteoporosis; Phenols (Class of compounds); Physiology; Postmenopausal women; Postmenopause; Product development; Randomized Controlled Trials as Topic; Sexual Behavior - drug effects; Sexual disorders; Sexual Dysfunction, Physiological - drug therapy; Sexual Dysfunction, Physiological - physiopathology; Sexual function; Study Protocol; Suppositories; Treatment Outcome; Vagina - drug effects; Vaginal Diseases - drug therapy; Vitamin D; Vitamin D - administration & dosage; Vitamin D vaginal suppository; Vitamins; Womens health; Iran; Vitamin D vaginal suppository; Menopause; Sexual function

Menopause is associated with changes in sexual function which are partly due to vaginal atrophy in response to estrogen reduction. Estrogen administration temporarily reduces the symptoms of vaginal dryness, but long-term exposure to this drug is likely to be associated with serious complications. C...