Efficacy of repetitive transcranial magnetic stimulation (rTMS) adjunctive therapy for major depressive disorder (MDD) after two antidepressant treatment failures: meta-analysis of randomized sham-controlled trials

• Published in: BMC psychiatry Vol. 23; no. 1; p. 545
• Main Authors: Vida, Róbert György, Sághy, Eszter, Bella, Richárd, Kovács, Sándor, Erdősi, Dalma, Józwiak-Hagymásy, Judit, Zemplényi, Antal, Tényi, Tamás, Osváth, Péter, Voros, Viktor
• Format: Journal Article
• Language: English
• Published: England BioMed Central 27.07.2023; BMC
• Subjects: Antidepressants; Clinical trials; Drug therapy; Efficacy; Investigations; Literature reviews; Magnetic fields; Major depressive disorder (MDD); Mental depression; Meta-analysis; Methodology; Psychiatry; Psychotherapy; Remission; Repetitive transcranial magnetic stimulation (rTMS); Response rates; Statistical analysis; Substance abuse treatment; Transcranial magnetic stimulation; Treatment-resistant depression (TRD); Validity; Efficacy; Repetitive transcranial magnetic stimulation (rTMS); Methodology; Treatment-resistant depression (TRD); Major depressive disorder (MDD); Meta-analysis

Several meta-analyses demonstrated the efficacy of unilateral High-Frequency Left-sided (HFL) repetitive Transcranial Magnetic Stimulation (rTMS) for individuals with Major Depressive Disorder (MDD); however, results are contradictory due to heterogeneity of the included studies. A systematic litera...