Cooled radiofrequency ablation provides extended clinical utility in the management of knee osteoarthritis: 12-month results from a prospective, multi-center, randomized, cross-over trial comparing cooled radiofrequency ablation to a single hyaluronic acid injection

• Published in: BMC musculoskeletal disorders Vol. 21; no. 1; pp. 363 - 11
• Main Authors: Chen, Antonia F., Khalouf, Fred, Zora, Keith, DePalma, Michael, Kohan, Lynn, Guirguis, Maged, Beall, Douglas, Loudermilk, Eric, Pingree, Matthew J., Badiola, Ignacio, Lyman, Jeffrey
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 09.06.2020; BioMed Central; BMC
• Subjects: Ablation; Ablation (Surgery); Acids; Adult; Aged; Aged, 80 and over; Algorithms; Antiarthritic agents; Arthritis; Cross-Over Studies; Data collection; Denervation; Female; Humans; Hyaluronic acid; Hyaluronic Acid - administration & dosage; Hylan; Injection; Injections, Intra-Articular; Knee; Knee Joint - drug effects; Knee Joint - innervation; Knee Joint - surgery; Male; Middle Aged; Musculoskeletal diseases; Narcotics; Non-surgical; Nonsteroidal anti-inflammatory drugs; Osteoarthritis; Osteoarthritis, Knee - therapy; Pain; Pain management; Pain Measurement; Physiology; Prospective Studies; Quality of Life; Questionnaires; Radiofrequency ablation; Radiofrequency Ablation - adverse effects; Radiofrequency Ablation - methods; Studies; Treatment Outcome; United States; United States; United States > US; Radiofrequency ablation; Non-surgical; Osteoarthritis; Denervation

Safe and effective non-surgical treatments are an important part of the knee osteoarthritis (OA) treatment algorithm. Cooled radiofrequency ablation (CRFA) and hyaluronic acid (HA) injections are two commonly used modalities to manage symptoms associated with knee OA. A prospective 1:1 randomized st...