Association between inflammation and skeletal muscle proteolysis, skeletal mass and strength in elderly heart failure patients and their prognostic implications

• Published in: BMC cardiovascular disorders Vol. 20; no. 1; pp. 228 - 9
• Main Authors: Koshikawa, Masayuki, Harada, Masahide, Noyama, Shunsuke, Kiyono, Ken, Motoike, Yuji, Nomura, Yoshihiro, Nishimura, Asuka, Izawa, Hideo, Watanabe, Eiichi, Ozaki, Yukio
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 15.05.2020; BioMed Central; BMC
• Subjects: Age; Angina pectoris; Blood pressure; Brain natriuretic peptide; C-reactive protein; Complications and side effects; Congestive heart failure; Correlation analysis; Creatinine; Cytokines; Elderly; Enzymes; Frailty; Geriatrics; Health aspects; Heart failure; Hospitalization; Immunoassay; Inflammation; Interleukin 6; Medical prognosis; Mortality; Musculoskeletal system; Older people; Patients; Physiological aspects; Population studies; Prognosis; Proteins; Proteolysis; Sarcopenia; Skeletal muscle; Survival analysis; Urine; Japan; Sarcopenia; Frailty; Elderly; Mortality

Inflammation and skeletal muscle wasting often coexist in elderly populations, but few studies have examined their relationship in elderly heart failure (HF) patients. This study examined the relationship between inflammation and increased skeletal muscle proteolysis, reduced skeletal mass and stren...