An initial study on the predictive value using multiple MRI characteristics for Ki-67 labeling index in glioma

• Published in: Journal of translational medicine Vol. 21; no. 1; pp. 119 - 11
• Main Authors: Du, Ningfang, Shu, Weiquan, Li, Kefeng, Deng, Yao, Xu, Xinxin, Ye, Yao, Tang, Feng, Mao, Renling, Lin, Guangwu, Li, Shihong, Fang, Xuhao
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 11.02.2023; BioMed Central; BMC
• Subjects: Analysis; Apparent diffusion coefficient; Biopsy; Brain cancer; Brain Neoplasms - diagnostic imaging; Brain Neoplasms - pathology; Brain tumors; Care and treatment; Cell cycle; Cell growth; Cell proliferation; Classification; Diagnosis; Diffusion coefficient; Diffusion Magnetic Resonance Imaging - methods; Diffusion-weighted magnetic resonance imaging; Edema; Glioma; Glioma - diagnostic imaging; Glioma - pathology; Glioma cells; Gliomas; Humans; Ki-67 Antigen; Ki-67 labeling index; Labeling; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Medical prognosis; Neoplasm Grading; Nervous system; Patients; Peritumoral edema; Retrospective Studies; Statistical analysis; Surgery; Testing; Tumors; Taiwan; Germany; Ki-67 labeling index; Glioma; Magnetic resonance imaging; Peritumoral edema; Diffusion-weighted magnetic resonance imaging; Apparent diffusion coefficient

Ki-67 labeling index (LI) is an important indicator of tumor cell proliferation in glioma, which can only be obtained by postoperative biopsy at present. This study aimed to explore the correlation between Ki-67 LI and apparent diffusion coefficient (ADC) parameters and to predict the level of Ki-67...