The effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review

• Published in: Critical care (London, England) Vol. 27; no. 1; pp. 78 - 20
• Main Authors: Li, Jie, Albuainain, Fai A., Tan, Wei, Scott, J. Brady, Roca, Oriol, Mauri, Tommaso
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 28.02.2023; BioMed Central; BMC
• Subjects: Administration, Intranasal; Adult; Analysis; Bias; Cannula; Carbon Dioxide; Care and treatment; Child; Chronic obstructive pulmonary disease; Complications and side effects; Consensus; Critical care; Evidence-based medicine; Flow settings; Flow visualization; Gases; Health aspects; High-flow nasal cannula; Humans; Lung diseases, Obstructive; Methods; Oxygen; Oxygen equipment (Medical care); Oxygen therapy; Oxygenation; Patients; Peak inspiratory flow; Pediatrics; Physiology; Prevention; Respiratory insufficiency; Review; Risk factors; Ventilation distribution; Ventilators; Italy; Oxygen therapy; Flow settings; Patient self-inflicted lung injury; High-flow nasal cannula; Oxygenation; Peak inspiratory flow; Ventilation distribution

During high-flow nasal cannula (HFNC) therapy, flow plays a crucial role in the physiological effects. However, there is no consensus on the initial flow settings and subsequent titration. Thus, we aimed to systematically synthesize the effects of flows during HFNC treatment. In this systematic revi...