Decreased acylated and total ghrelin levels in bipolar disorder patients recovering from a manic episode

• Published in: BMC psychiatry Vol. 22; no. 1; pp. 209 - 8
• Main Authors: Abdel Aziz, Karim, Al-Mugaddam, Fadwa, Sugathan, Subi, Saseedharan, Prashanth, Jouini, Tarek, Elamin, Mohamed Elhassan, Moselhy, Hamdy, Aly El-Gabry, Dina, Arnone, Danilo, Karam, Sherif M.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 21.03.2022; BioMed Central; BMC
• Subjects: Acylated ghrelin; Affective disorders; Antibodies; Antipsychotic drugs; Antipsychotics; Bipolar disorder; Body mass index; Body weight gain; Care and treatment; Des-acylated ghrelin; Diagnosis; Dosage and administration; Drug therapy; Enzyme-linked immunosorbent assay; Euthymia; Food; Ghrelin; Health aspects; Hunger; Mania; Measurement; Mental disorders; Metabolism; Patients; Peptides; Psychiatry; Psychosis; Risk factors; Total ghrelin; United Kingdom; United States > US; Des-acylated ghrelin; Mania; Bipolar disorder; Total ghrelin; Acylated ghrelin; Euthymia

To date, only few studies have investigated ghrelin levels in bipolar disorders, and all have exclusively measured acylated ghrelin, with none investigating total ghrelin (acylated and des-acylated). We aimed to investigate peripheral levels of acylated and total ghrelin in subjects experiencing a m...