Genetic background influences arterial vasomotor function in male and female mice

• Published in: Physiological reports Vol. 11; no. 19; pp. e15824 - n/a
• Main Authors: Holly, Dylan, Kim, Hyoseon, Woodman, Christopher R., Massett, Michael P.
• Format: Journal Article
• Language: English
• Published: Oxford John Wiley & Sons, Inc 01.10.2023; John Wiley and Sons Inc; Wiley
• Subjects: Adrenergic receptors; Age; Aorta; Arginine; Atherosclerosis; Blood vessels; Cardiovascular disease; Carotid artery; Contractility; Coronary vessels; Endothelium; Females; Femoral artery; Gender differences; inbred mice; Laboratory animals; Males; NG-Nitroarginine methyl ester; Nitric oxide; Nitric-oxide synthase; Original; Phenylephrine; Physiology; sex differences; Single-nucleotide polymorphism; Sodium nitroprusside; Thorax; Vasodilation; Vasodilators; Veins & arteries; United States > US; Texas

The purpose of this study was to assess the influence of genetic background and sex on nitric oxide (NO)‐mediated vasomotor function in arteries from different vascular territories. Vasomotor function was assessed in thoracic aorta, abdominal aorta, carotid arteries, and femoral arteries from the fo...