OptM: estimating the optimal number of migration edges on population trees using Treemix

• Published in: Biology methods and protocols Vol. 6; no. 1; p. bpab017
• Main Author: Fitak, Robert R
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 2021
• Subjects: Bioinformatics; Biology; Datasets; Domestic animals; Gene frequency; Genomes; Genomics; Innovations; Migration; Population; Population genetics; Simulation; Software packages; Trees; population genomics; SNPs; likelihood; structure

Abstract The software Treemix has become extensively used to estimate the number of migration events, or edges (m), on population trees from genome-wide allele frequency data. However, the appropriate number of edges to include remains unclear. Here, I show that an optimal value of m can be inferred...