Erk2 Phosphorylation of Drp1 Promotes Mitochondrial Fission and MAPK-Driven Tumor Growth - Kashatus, Jennifer A.; Nascimento, Aldo; Myers, Lindsey J.; Sher, Annie; Byrne, Frances L.; Hoehn, Kyle L.; Counter, Christopher M.; Kashatus, David F. (Molecular cell, 2015)
Keywords: adenocarcinoma; Animals; Benzamides - pharmacology; Cell Line, Tumor; Diphenylamine - analogs & derivatives; Diphenylamine - pharmacology; Gene Knockdown Techniques; GTP Phosphohydrolases - genetics; GTP Phosphohydrolases - metabolism; guanosinetriphosphatase; HEK293 Cells; HeLa Cells; Humans; Mice; Mice, Nude; Microtubule-Associated Proteins - genetics; Microtubule-Associated Proteins - metabolism; mitochondria; Mitochondrial Dynamics - drug effects; Mitochondrial Proteins - genetics; Mitochondrial Proteins - metabolism; mitogen-activated protein kinase; Mitogen-Activated Protein Kinase 1 - metabolism; Neoplasms, Experimental - metabolism; pancreatic neoplasms; Pancreatic Neoplasms - metabolism; phenotype; Phosphorylation; ras Proteins - metabolism; serine; Serine - metabolism