Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein - Pak, Chi W.; Kosno, Martyna; Holehouse, Alex S.; Padrick, Shae B.; Mittal, Anuradha; Ali, Rustam; Yunus, Ali A.; Liu, David R.; Pappu, Rohit V.; Rosen, Michael K. (Molecular cell, 2016)
Keywords: amino acid composition; Amino Acid Sequence; Animals; Cell Nucleus - chemistry; Cell Nucleus - metabolism; Computer Simulation; droplets; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; hydrophobicity; in vitro studies; Intrinsically Disordered Proteins - chemistry; Intrinsically Disordered Proteins - genetics; Intrinsically Disordered Proteins - metabolism; Membrane Proteins - chemistry; Membrane Proteins - genetics; Membrane Proteins - metabolism; Mice; Models, Molecular; mutagenesis; Mutation; organelles; Organelles - chemistry; Organelles - metabolism; Protein Domains; proteins; Proteomics - methods; separation; Static Electricity; Structure-Activity Relationship; Surface Properties; Time Factors; Transfection