Recombination between vaccine and field strains of canine parvovirus is revealed by isolation of virus in canine and feline cell cultures

• Published in: Journal of Veterinary Medical Science Vol. 70; no. 12; pp. 1305 - 1314
• Main Authors: Mochizuki, M.(Kyoritsu Seiyaku Corp., Tokyo (Japan)), Ohshima, T, Une, Y, Yachi, A
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 01.12.2008; Japan Science and Technology Agency
• Subjects: Amino Acid Sequence; Animals; CAMPO; CANINE PARVOVIRUS; Capsid Proteins - chemistry; Capsid Proteins - genetics; Cats; CELL CULTURE; Cell Line; CHAMP; CHIEN; CULTIVO DE CELULAS; CULTURE DE CELLULE; dog; Dog Diseases - immunology; Dog Diseases - virology; DOGS; FIELDS; Kidney - cytology; Mutation; PARVOVIRIDAE; Parvoviridae Infections - veterinary; Parvoviridae Infections - virology; parvovirus; PARVOVIRUS CANIN; PARVOVIRUS CANINO; Parvovirus, Canine - classification; Parvovirus, Canine - genetics; Parvovirus, Canine - isolation & purification; PERRO; Reassortant Viruses - genetics; RECOMBINACION; RECOMBINAISON; RECOMBINATION; VACCIN; VACCINES; VACUNA; Viral Vaccines - adverse effects; Virus Cultivation

Canine parvovirus type 2 (CPV) is a pathogen that causes severe hemorrhagic gastroenteritis with a high fatality rate in pups worldwide. Since CPV emerged in the late 1970s, its origin has been explored with the conclusion that CPV originated from feline panleukopenia virus or a closely related viru...