An investigation of statistical power for continuous arterial spin labeling imaging at 1.5 T

• Published in: NeuroImage (Orlando, Fla.) Vol. 39; no. 3; pp. 1246 - 1256
• Main Authors: Asllani, Iris, Borogovac, Ajna, Wright, Clinton, Sacco, Ralph, Brown, Truman R., Zarahn, Eric
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2008; Elsevier Limited
• Subjects: Acquisitions & mergers; Aged; Algorithms; Analysis of Variance; ASL; Brain; CBF; Cerebral Arteries - anatomy & histology; Cerebrovascular Circulation - physiology; Cohort Studies; Echo-Planar Imaging - statistics & numerical data; fMRI; Humans; Image Processing, Computer-Assisted - statistics & numerical data; Intersubject variance; Intrasubject variance; Medical imaging; Reproducibility of Results; Sample variance; Spin Labels; Statistical power; Studies; fMRI; ASL; Intrasubject variance; Statistical power; CBF; Intersubject variance

Variance estimates can be used in conjunction with scientifically meaningful effect sizes to design experiments with type II error control. Here we present estimates of intra- and inter-subject variances for region of interest (ROI) from resting cerebral blood flow (CBF) maps obtained using whole br...