Bacterial 16S Sequence Analysis of Severe Caries in Young Permanent Teeth

• Published in: Journal of Clinical Microbiology Vol. 48; no. 11; pp. 4121 - 4128
• Main Authors: Gross, Erin L, Leys, Eugene J, Gasparovich, Stephen R, Firestone, Noah D, Schwartzbaum, Judith A, Janies, Daniel A, Asnani, Kashmira, Griffen, Ann L
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.11.2010; American Society for Microbiology (ASM)
• Subjects: Adolescent; Bacteria; Bacteria - classification; Bacteria - genetics; Bacteria - metabolism; Bacteriology; Biodiversity; Biological and medical sciences; Campylobacter rectus; Capnocytophaga gingivalis; Carboxylic Acids - metabolism; Child; Cluster Analysis; Corynebacterium matruchotii; Dental Caries - microbiology; DNA, Bacterial - chemistry; DNA, Bacterial - genetics; DNA, Ribosomal - chemistry; DNA, Ribosomal - genetics; Eubacterium; Female; Fundamental and applied biological sciences. Psychology; Humans; Lactobacillus; Male; Metagenome; Microbiology; Miscellaneous; Neisseria; Phylogeny; Propionibacterium; RNA, Ribosomal, 16S - genetics; Sequence Analysis, DNA; Streptococcus gordonii; Streptococcus mitis; Streptococcus mutans; Tooth - microbiology; Bacteria; Tooth

Previous studies have confirmed the association of the acid producers Streptococcus mutans and Lactobacillus spp. with childhood caries, but they also suggested these microorganisms are not sufficient to explain all cases of caries. In addition, health-associated bacterial community profiles are not...