Estimation of the proviral load in Japanese Black cattle infected with bovine leukemia virus by statistical modeling

• Published in: Journal of Veterinary Medical Science Vol. 86; no. 2; pp. 135 - 140
• Main Authors: KOREEDA, Terunori, IINO, Mei, EITOKU, Rikako, IWAMOTO, Jiro, SHIBATA, Shoichi
• Format: Journal Article
• Language: English
• Published: Japan JAPANESE SOCIETY OF VETERINARY SCIENCE 2024; Japan Science and Technology Agency; The Japanese Society of Veterinary Science
• Subjects: B-cell lymphoma; bovine leukemia virus; Bovine leukosis; Cattle; Cell number; enzootic bovine leukosis; Epidemiology; Genomes; Leukemia; Leukosis; Lymphocytes; Lymphocytes B; Lymphocytosis; Mathematical models; persistent lymphocytosis; proviral load; Regression analysis; statistical modeling; statistical modeling; enzootic bovine leukosis; bovine leukemia virus; persistent lymphocytosis; proviral load

Enzootic bovine leukosis (EBL) is B-cell lymphoma in cattle caused by bovine leukemia virus (BLV) infection. The incidence of EBL has been increasing since 1998 in Japan, resulting in significant economic losses for farms. The BLV genome integrates with the host genome as provirus, leading to sustai...