Optical spectroscopy of the bladder washout fluid to optimize fluorescence cystoscopy with Hexvix

• Published in: Journal of biomedical optics Vol. 19; no. 9; p. 097002
• Main Authors: Martoccia, Carla, Zellweger, Matthieu, Lovisa, Blaise, Jichlinski, Patrice, van den Bergh, Hubert, Wagnières, Georges
• Format: Journal Article
• Language: English
• Published: United States Society of Photo-Optical Instrumentation Engineers 01.09.2014
• Subjects: Adult; Aged; Aminolevulinic Acid - analogs & derivatives; Aminolevulinic Acid - chemistry; Bladder; Cystoscopy - methods; Excitation; Female; Fluid dynamics; Fluid flow; Fluids; Fluorescence; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Spectrometry, Fluorescence - methods; Spectroscopy; Temperature; Urinary Bladder - surgery; Urine; Urine - chemistry; background fluorescence; photodetection; fluorescence spectroscopy; urinary bladder
• ISSN: 1083-3668; 1560-2281; 1560-2281
• DOI: 10.1117/1.JBO.19.9.097002

Fluorescence cystoscopy enhances detection of early bladder cancer. Water used to inflate the bladder during the procedure rapidly contains urine, which may contain fluorochromes. This frequently degrades fluorescence images. Samples of bladder washout fluid (BWF) or urine were collected (15 subject...