The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations - Chen, Liang; Chen, Jia-Yu; Huang, Yi-Jou; Gu, Ying; Qiu, Jinsong; Qian, Hao; Shao, Changwei; Zhang, Xuan; Hu, Jing; Li, Hairi; He, Shunmin; Zhou, Yu; et al. (Molecular cell, 2018)
Keywords: alleles; amino acid sequences; ataxia (disorder); blood; DNA-directed RNA polymerase; gene overexpression; genome instability; MDS; mutants; mutation; neoplasms; phenotype; R-loops; ribonucleases; RNA; splicing factor mutations; transcription (genetics); transcriptional elongation factors; R-loops; genome instability; MDS; splicing factor mutations