Amanita muscaria extract potentiates production of proinflammatory cytokines by dsRNA-activated human microglia

• Published in: Frontiers in pharmacology Vol. 14; p. 1102465
• Main Authors: Wagner, Ashley, Pehar, Marcus, Yan, Zhimin, Kulka, Marianna
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media 12.04.2023; Frontiers Media S.A
• Subjects: cytokines; HMC3; HMC3 cells; inflammation; microglia; Pharmacology; toll-like receptor; trehalose; HMC3 cells; HMC3; inflammation; cytokines; toll-like receptor; trehalose; microglia

Recent interest in mushrooms and their components as potential therapies for mental health, along with recent government and health authority approvals, has necessitated a more comprehensive understanding of their effects on the cellular microenvironment of the brain. Amanita muscaria has been inges...