Synthesis and evaluation of novel 1-(((6-substitutedbenzo[d]thiazol-2-yl)amino)(heteroaryl)methyl)naphthalen-2-ol as pesticidal agents

• Published in: Journal of enzyme inhibition and medicinal chemistry Vol. 37; no. 1; pp. 641 - 651
• Main Authors: Shang, Junfeng, Li, Yuxin, Yang, Na, Xiong, Lixia, Wang, Baolei
• Format: Journal Article
• Language: English
• Published: ABINGDON Taylor & Francis 01.12.2022; Taylor & Francis Ltd; Taylor & Francis Group
• Subjects: Agricultural production; Agrochemicals; Bioassays; Biochemistry & Molecular Biology; Calcium imaging; Chemistry, Medicinal; Chromatography; Enzymes; Laboratories; Lethality; Life Sciences & Biomedicine; Novel β-naphthol derivatives; Organic chemistry; pesticidal activity; Pharmacology & Pharmacy; Research Paper; ryanodine receptor; Science & Technology; Solvents; structure-activity relationship; synthesis; synthesis; INSECTICIDAL ACTIVITIES; DESIGN; POTENT; Novel beta-naphthol derivatives; pesticidal activity; ryanodine receptor; structure-activity relationship; DERIVATIVES; ANTHRANILIC DIAMIDE; Novel β-naphthol derivatives

To discover new agrochemicals with prominent pesticidal properties, a series of novel β-naphthol derivatives containing benzothiazolylamino and various heteroaryl groups (8a-q) were efficiently synthesised via Betti reaction. The bioassay results showed that most of the synthesised compounds exhibit...