The identification of a cis-acting element involved in cyclic 3‘,5‘-adenosine monophosphate regulation of bovine vasopressin gene expression

• Published in: The Journal of biological chemistry Vol. 267; no. 30; pp. 21746 - 21752
• Main Authors: Pardy, K, Adan, R.A., Carter, D.A., Seah, V, Burbach, J.P., Murphy, D
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Elsevier Inc 25.10.1992; American Society for Biochemistry and Molecular Biology
• Subjects: Animals; Base Sequence; Biological and medical sciences; Cattle; Cells, Cultured; Cyclic AMP - physiology; DNA; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation; Genes. Genome; Molecular and cellular biology; Molecular genetics; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Sequence Homology, Nucleic Acid; Transcription Factors - metabolism; Transfection; Vasopressins - genetics; Vertebrata; Mammalia; Transfection; Gene; Bovine; Footprinting technique; Cyclic AMP; Regulatory sequence; Artiodactyla; Gene expression; Ungulata; Vasopressin

Cyclic adenosine 3‘,5‘-monophosphate (cAMP) has been implicated as an intracellular messenger mediating osmotic regulation of expression of the gene encoding the neuropeptide vasopressin (VP) in the hypothalamus. We have used a heterologous transient transfection system to demonstrate that cAMP regu...