An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides

• Published in: Drug design, development and therapy Vol. 9; no. default; pp. 33 - 78
• Main Authors: Zhou, Shu-Feng, Cheng, Jiang, Zhou, Zhi-Wei, Sheng, Hui-Ping, He, Lan-Jie, Fan, Xue-Wen, He, Zhi-Xu, Sun, Tao, Zhang, Xueji, Gu, Ling, Cao, Chuanhai, Zhao, Ruan Jin
• Format: Journal Article
• Language: English
• Published: New Zealand Dove Medical Press Limited 2015; Taylor & Francis Ltd; Dove Press; Dove Medical Press
• Subjects: Animals; anti-aging; Anticancer properties; Antineoplastic Agents, Phytogenic - chemistry; Antineoplastic Agents, Phytogenic - isolation & purification; Antineoplastic Agents, Phytogenic - pharmacology; antioxidant; Antioxidants - chemistry; Antioxidants - isolation & purification; Antioxidants - pharmacology; Apoptosis; Apoptosis - drug effects; Berries; Biocompatibility; Blood Glucose - drug effects; Cancer; Cell cycle; Cell proliferation; Cell Proliferation - drug effects; Chemotherapy; Dietary supplements; Evidence-based medicine; Excitotoxicity; Fruits; Glaucoma; Glucose metabolism; Goji berries; Health aspects; Health promotion; Humans; Hypoglycemic Agents - chemistry; Hypoglycemic Agents - isolation & purification; Hypoglycemic Agents - pharmacology; Insulin; Insulin secretion; Interleukin 2; Irradiation; Ischemia; ischemic/reperfusion injury; Lycium; Lycium - chemistry; Lycium barbarum; mechanism; Medical research; Medicinal plants; Medicine, Experimental; Metabolism; Mice; natural killer; Neurogenesis; Neurotoxicity; Organic chemistry; Pancreas; Pharmacology; Polysaccharides; Polysaccharides - chemistry; Polysaccharides - isolation & purification; Polysaccharides - pharmacology; Radiation; Reperfusion; Reproduction (biology); Retina; Retinal ganglion cells; Review; Saccharides; Sensitizing; Signs and symptoms; Substrate Specificity; Subventricular zone; T cell; Toxicity; β-Amyloid; anti-aging; antioxidant; natural killer; T cell; ischemic/reperfusion injury; apoptosis; cancer; mechanism; chemotherapy
• ISSN: 1177-8881; 1177-8881
• DOI: 10.2147/DDDT.S72892

Lycium barbarum berries, also named wolfberry, Fructus lycii, and Goji berries, have been used in the People's Republic of China and other Asian countries for more than 2,000 years as a traditional medicinal herb and food supplement. L. barbarum polysaccharides (LBPs) are the primary active com...