Effects of Polyphenols on Glucose‐Induced Metabolic Changes in Healthy Human Subjects and on Glucose Transporters

• Published in: Molecular nutrition & food research Vol. 66; no. 21; pp. e2101113 - n/a
• Main Author: Williamson, Gary
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.11.2022; John Wiley and Sons Inc
• Subjects: Acute effects; Amino acids; apples; beta-galactosidase; beverages; Blood; Blood glucose; Blood Glucose - metabolism; digestive enzymes; dihydrochalcone; Fatty acids; flavonoid; Food consumption; food research; Glucose; Glucose - metabolism; Glucose Transport Proteins, Facilitative; Glucose transporter; Glucose Transporter Type 2; Healthy Volunteers; Hormones; Humans; Incretins; Insulin; Insulin - metabolism; Intestine; Lactase; Metabolism; microvilli; nutrition; OGTT; Oleuropein; olives; Oxidative stress; Phenolic compounds; Phenols; Phlorhizin - pharmacology; Polyphenols; Polyphenols - chemistry; Polyphenols - pharmacology; post prandial; Review; Reviews; secretin; Small intestine; sugar; flavonoid; insulin; OGTT; sugar; dihydrochalcone; post prandial

Dietary polyphenols interact with glucose transporters in the small intestine and modulate glucose uptake after food or beverage consumption. This review assesses the transporter interaction in vitro and how this translates to an effect in healthy volunteers consuming glucose. As examples, the apple...