High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency

• Published in: Brain & development (Tokyo. 1979) Vol. 43; no. 6; pp. 680 - 687
• Main Authors: Tanigawa, Junpei, Nabatame, Shin, Tominaga, Koji, Nishimura, Yoko, Maegaki, Yoshihiro, Kinosita, Taroh, Murakami, Yoshiko, Ozono, Keiichi
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.06.2021
• Subjects: Epilepsy; Inherited glycosylphosphatidylinositol deficiencies; PIGL; PIGO; Pyridoxine; Vitamin B6; Pyridoxine; PIGL; PIGO; Epilepsy; Inherited glycosylphosphatidylinositol deficiencies; Vitamin B6

We aimed to assess the efficacy and safety of high-dose pyridoxine treatment for seizures and its effects on development in patients with inherited glycosylphosphatidylinositol deficiencies (IGDs). In this prospective open-label multicenter pilot study, we enrolled patients diagnosed with IGDs using...