Therapeutic effect of high-dose green tea extract on weight reduction: A randomized, double-blind, placebo-controlled clinical trial

• Published in: Clinical nutrition (Edinburgh, Scotland) Vol. 35; no. 3; pp. 592 - 599
• Main Authors: Chen, I-Ju, Liu, Chia-Yu, Chiu, Jung-Peng, Hsu, Chung-Hua
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2016
• Subjects: adiponectin; Adult; adverse effects; Anti-Obesity Agents - adverse effects; Anti-Obesity Agents - therapeutic use; Body Mass Index; Camellia sinensis - chemistry; Catechin - adverse effects; Catechin - analogs & derivatives; Catechin - therapeutic use; cholesterol; clinical trials; Dietary Supplements - adverse effects; Double-Blind Method; EGCG 4; Epigallocatechin gallate; Female; Food Preservation; Gastroenterology and Hepatology; ghrelin; Ghrelin - antagonists & inhibitors; Ghrelin - blood; Ghrelin - secretion; green tea; Green tea extract; Humans; Hyperlipidemias - blood; Hyperlipidemias - diet therapy; Hypolipidemic Agents - adverse effects; Hypolipidemic Agents - therapeutic use; leptin; lipid composition; low density lipoprotein; Middle Aged; Obese women; obesity; Obesity, Abdominal - blood; Obesity, Abdominal - diet therapy; Oxidation-Reduction; Patient Dropouts; placebos; Plant Extracts - adverse effects; Plant Extracts - therapeutic use; Plant Leaves - chemistry; secretion; Taiwan; therapeutics; Waist Circumference; Weight Loss; women; Green tea extract; Epigallocatechin gallate; Obese women; EGCG 4

To examine the effect and safety of high-dose green tea extract (Epigallocatechin gallate, EGCG) at a daily dosage of 856.8 mg on weight reduction and changes of lipid profile and obesity-related hormone peptides in women with central obesity. We conducted a randomized, double-blind trial registered...