Quality Markers’ Discovery and Quality Evaluation of Jigucao Capsule Using UPLC-MS/MS Method

• Published in: Molecules (Basel, Switzerland) Vol. 28; no. 6; p. 2494
• Main Authors: He, Yanmei, Wu, Fangfang, Tan, Zhien, Zhang, Mengli, Li, Taiping, Zhang, Aihua, Miao, Jianhua, Ou, Min, Long, Lihuo, Sun, Hui, Wang, Xijun
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.03.2023; MDPI
• Subjects: Analysis; Bile ducts; Cholecystitis; Chromatography, High Pressure Liquid - methods; Chromatography, Liquid; Drugs, Chinese Herbal - chemistry; Gallbladder diseases; Hepatitis; jigucao capsule; Liver; Mass spectrometry; Metabolites; Methods; Oral administration; Pharmacodynamics; Quality Control; quality evaluation; quality markers; serum pharmacochemistry; Software; Tandem Mass Spectrometry - methods; Traditional Chinese medicine; ultra-high-performance liquid chromatography-mass spectrometry; Massachusetts; China; quality evaluation; serum pharmacochemistry; ultra-high-performance liquid chromatography-mass spectrometry; jigucao capsule; quality markers

Jigucao capsules (JGCC) have the effects of soothing the liver and gallbladder and clearing heat and detoxification. It is a good medicine for treating acute and chronic hepatitis cholecystitis with damp heat of the liver and gallbladder. However, the existing quality standard of JGCC does not have...