Acute effects of 1-octen-3-ol, a microbial volatile organic compound (MVOC)—An experimental study

• Published in: Toxicology letters Vol. 181; no. 3; pp. 141 - 147
• Main Authors: Wålinder, Robert, Ernstgård, Lena, Norbäck, Dan, Wieslander, Gunilla, Johanson, Gunnar
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 01.10.2008; Amsterdam Elsevier Science
• Subjects: 1-Octen-3-ol; Adult; Air Microbiology - standards; Air Pollutants - toxicity; Biological and medical sciences; Biomarkers - analysis; Blinking - drug effects; Chamber study; Eye - drug effects; Female; Humans; Indoor environment; Inhalation Exposure - adverse effects; Inhalation Exposure - analysis; Irritants - toxicity; Linoleic acid; Male; Medical sciences; MEDICIN; MEDICINE; Middle Aged; Mould; Nasal Lavage Fluid - chemistry; Octanols - toxicity; Respiratory System - drug effects; Rhinometry, Acoustic; Spirometry; Surveys and Questionnaires; Toxicity Tests, Acute; Toxicology; Vital Capacity - drug effects; Volatile organic compound; Young Adult; BUT; NIOSH; Volatile organic compound; Indoor environment; CO; MPO; VC; 1-Octen-3-ol; Linoleic acid; PEF; FVC; ECP; ACGIH; OSHA; Mould; EMG; TWA; Chamber study; Acute; 1 -Octen-3-oI; Polyunsaturated fatty acid; Lipids; Environment; Experimental study

Acute effects were assessed from exposure to a common volatile compound of microbial origin, the aliphatic alcohol 1-octen 3-ol (octenol). Twenty-nine volunteers performed symptom reports, measurement of blink frequency by electromyography, measurement of the eye break-up time, vital staining of the...