Advances in Nucleic Acid Assays for Infectious Disease: The Role of Microfluidic Technology

• Published in: Molecules (Basel, Switzerland) Vol. 29; no. 11; p. 2417
• Main Authors: Wang, Yiran, Chen, Jingwei, Yang, Zhijin, Wang, Xuanyu, Zhang, Yule, Chen, Mengya, Ming, Zizhen, Zhang, Kaihuan, Zhang, Dawei, Zheng, Lulu
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.06.2024; MDPI
• Subjects: Accuracy; Acids; Communicable diseases; Communicable Diseases - diagnosis; COVID-19; COVID-19 - diagnosis; COVID-19 - virology; CRISPR; Dengue - diagnosis; Dengue fever; Disease transmission; Ebola virus; Efficiency; Epidemics; Extracellular vesicles; Fatalities; Genomes; high throughput; Humans; infectious disease; Methicillin; Methods; Microfluidic Analytical Techniques - methods; microfluidic system; Microfluidics; Microfluidics - methods; Microorganisms; Molecular biology; Molecular Diagnostic Techniques - methods; Nucleic Acid Amplification Techniques - methods; nucleic acid assay; Pandemics; Public health; Quantitative analysis; rapid diagnosis; Review; SARS-CoV-2 - genetics; SARS-CoV-2 - isolation & purification; Severe acute respiratory syndrome coronavirus 2; Smart phones; Staphylococcus infections; Technology; Thermal cycling; Zika virus; Zika Virus - genetics; Zika Virus - isolation & purification; Zika Virus Infection - diagnosis; Zika Virus Infection - virology; Netherlands; microfluidic system; infectious disease; high throughput; rapid diagnosis; nucleic acid assay

Within the fields of infectious disease diagnostics, microfluidic-based integrated technology systems have become a vital technology in enhancing the rapidity, accuracy, and portability of pathogen detection. These systems synergize microfluidic techniques with advanced molecular biology methods, in...