SARS-CoV-2 vaccine effectiveness against infection, symptomatic and severe COVID-19: a systematic review and meta-analysis

• Published in: BMC infectious diseases Vol. 22; no. 1; pp. 439 - 12
• Main Authors: Ssentongo, Paddy, Ssentongo, Anna E., Voleti, Navya, Groff, Destin, Sun, Ashley, Ba, Djibril M., Nunez, Jonathan, Parent, Leslie J., Chinchilli, Vernon M., Paules, Catharine I.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 07.05.2022; BioMed Central; BMC
• Subjects: Age; Bias; Clinical trials; Coronaviruses; COVID-19; COVID-19 vaccines; Estimates; Evolution; Infections; Infectious diseases; Literature reviews; Meta-analysis; mRNA vaccines; Public health; Quality assessment; Risk assessment; Severe acute respiratory syndrome coronavirus 2; Vaccination; Vaccine effectiveness; Vaccine efficacy; Vaccines; Viral diseases; Waning immunity; Web portals; United States; United States > US; COVID-19; Waning immunity; Vaccine effectiveness

The temporal evolution of SARS-CoV-2 vaccine efficacy and effectiveness (VE) against infection, symptomatic, and severe COVID-19 is incompletely defined. The temporal evolution of VE could be dependent on age, vaccine types, variants of the virus, and geographic region. We aimed to conduct a systema...