Shutoff of RNA Polymerase II Transcription by Poliovirus Involves 3C Protease-Mediated Cleavage of the TATA-Binding Protein at an Alternative Site: Incomplete Shutoff of Transcription Interferes with Efficient Viral Replication

• Published in: Journal of Virology Vol. 79; no. 15; pp. 9702 - 9713
• Main Authors: KUNDU, Pallob, RAYCHAUDHURI, Santanu, TSAI, Weimin, DASGUPTA, Asim
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.08.2005
• Subjects: 3C Viral Proteases; Amino Acid Sequence; Biological and medical sciences; Cysteine Endopeptidases - metabolism; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation, Viral; Glutamine; HeLa Cells - metabolism; Humans; Microbiology; Miscellaneous; Molecular Sequence Data; Poliovirus - enzymology; Poliovirus - genetics; Poliovirus - physiology; Proteins - genetics; RNA Polymerase II - metabolism; Serine; TATA-Box Binding Protein - genetics; TATA-Box Binding Protein - metabolism; Transcription, Genetic; Viral Proteins - metabolism; Virology; Virus Replication; Virus-Cell Interactions; Microbiology; Transcription; Enzyme; Cysteine endopeptidases; Transferases; Binding site; DNA-directed RNA polymerase; Virology; Peptidases; Binding protein; Nucleotidyltransferases; Hydrolases; Replication; Picornain 3C

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