Scalp Microbiome Dynamics Can Contribute to the Clinical Effect of a Novel Antiseborrheic Dermatitis Shampoo Containing Patented Antifungal Actives: A Randomized Controlled Study

• Published in: Dermatology and therapy Vol. 15; no. 8; pp. 2077 - 2097
• Main Authors: Maître, Martine, Baradat, Sophie, Froliger, Mélanie, Turlier, Virginie, Simcic-Mori, Aimée, Gravier, Eléonore, Géniès, Camille, Lauze, Christophe, Huyghe, Céline, Noustens, Anaïs, Alvarez-Georges, Sandrine, Marinescu, Rasvan, Reygagne, Pascal, Bessou-Touya, Sandrine, Mengeaud, Valérie, Duplan, Hélène
• Format: Journal Article
• Language: English
• Published: Cheshire Springer Healthcare 01.08.2025; Springer; Springer Nature B.V; Adis, Springer Healthcare
• Subjects: Anti-dandruff shampoo; Dandruff; Dermatitis; Dermatology; Dosage and administration; Drug therapy; Erythema; Fungal and bacterial populations; Health aspects; Internal Medicine; Intervention; Laboratories; Medicine; Medicine & Public Health; Microbiota; Microbiota (Symbiotic organisms); Microbiota diversity; Oral and Maxillofacial Surgery; Original Research; Patient outcomes; Plastic Surgery; Pruritus; Quality of Life Research; Scalp microbiota; Seborrhea; Seborrheic dermatitis/scalp seborrheic dermatitis; Shampoos; Testing; Topical medication; France; Fungal and bacterial populations; Seborrheic dermatitis/scalp seborrheic dermatitis; Scalp microbiota; Ciclopirox olamine; Anti-dandruff shampoo; Piroctone olamine; Dandruff; Microbiota diversity; Ascomycota

Introduction Scalp seborrheic dermatitis (SD) can cause physical discomfort and social embarrassment in affected individuals. Mild-to-moderate scalp SD can be managed using topical products with antifungal, antiinflammatory, and keratolytic properties. Methods A two-phase, randomized, controlled stu...