Evaluation of correlates of protection against influenza A(H3N2) and A(H1N1)pdm09 infection: Applications to the hospitalized patient population

• Published in: Vaccine Vol. 37; no. 10; pp. 1284 - 1292
• Main Authors: Petrie, Joshua G., Martin, Emily T., Truscon, Rachel, Johnson, Emileigh, Cheng, Caroline K., McSpadden, E.J., Malosh, Ryan E., Lauring, Adam S., Lamerato, Lois E., Eichelberger, Maryna C., Ferdinands, Jill M., Monto, Arnold S.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 28.02.2019; Elsevier Limited
• Subjects: Acute Disease; Adolescent; Adult; Adults; Age; Aged; Antibodies, Viral - blood; Comorbidity; Correlates of protection; Demographics; Enrollments; Exo-a-sialidase; Female; Frailty; Hemagglutination; Hemagglutination Inhibition Tests; Hemagglutinin; Hospitalization - statistics & numerical data; Hospitals; Humans; Illnesses; Immune status; Infections; Influenza; Influenza A; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza vaccine; Influenza Vaccines - administration & dosage; Influenza Vaccines - immunology; Influenza, Human - immunology; Influenza, Human - prevention & control; Inpatient; Male; Medical laboratories; Medical records; Middle Aged; Neuraminidase; Polymerase chain reaction; Public health; Respiratory diseases; Respiratory Tract Infections - virology; Seasons; Serology; Signs and symptoms; Vaccination; Vaccine efficacy; Vaccines; Vaccines, Attenuated - immunology; Vaccines, Inactivated - immunology; Viruses; Young Adult; Northern Hemisphere; Detroit Michigan; United States > US; Texas; China; Hong Kong China; California; Ann Arbor Michigan; CDC; OR; Hemagglutinin; CI; Serology; GMT; VE; HAI; Correlates of protection; RT-PCR; Influenza; NAI; Neuraminidase; Inpatient; Influenza vaccine

•Serum collected at hospital admission can be used to assess influenza protection.•There was no trend in antibody among influenza cases by day of collection (0–10).•Inpatients who received influenza vaccination had more antibody than unvaccinated.•Associations between antibody and infection parallel...