Impact of TRPV1 on Pathogenesis and Therapy of Neurodegenerative Diseases

• Published in: Molecules (Basel, Switzerland) Vol. 29; no. 1; p. 181
• Main Authors: Wang, Wenxin, Sun, Tao
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 28.12.2023; MDPI
• Subjects: Advertising executives; Agonists; Alzheimer Disease - drug therapy; Alzheimer's disease; Animals; antagonists; Antineoplastic Agents; Autophagy; Binding sites; Biological Products; Brain research; Dementia; Development and progression; Disease; Health aspects; Kinases; Memory; Multiple sclerosis; Nervous system; Nervous system diseases; neurodegenerative diseases; Neurodegenerative Diseases - drug therapy; neuroinflammation; Parkinson Disease; Pathogenesis; Pathology; Physiology; Proteins; Review; Signal transduction; TRPV1; antagonists; neurodegenerative diseases; agonists; TRPV1; neuroinflammation

Transient receptor potential vanilloid 1 (TRPV1) is a transmembrane and non-selective cation channel protein, which can be activated by various physical and chemical stimuli. Recent studies have shown the strong pathogenetic associations of TRPV1 with neurodegenerative diseases (NDs), in particular...