Staggered overdose pattern and delay to hospital presentation are associated with adverse outcomes following paracetamol‐induced hepatotoxicity - Craig, Darren G. N.; Bates, Caroline M.; Davidson, Janice S.; Martin, Kirsty G.; Hayes, Peter C.; Simpson, Kenneth J. (British journal of clinical pharmacology, 2012)
Keywords: Acetaminophen - poisoning; acute; Adult; Analgesics, Non-Narcotic - poisoning; Biological and medical sciences; Chemical and Drug Induced Liver Injury - etiology; Chemical and Drug Induced Liver Injury - mortality; Cohort Studies; Drug Overdose - etiology; Drug Overdose - mortality; drug‐induced liver injury; Female; Gastroenterology. Liver. Pancreas. Abdomen; hepatic encephalopathy; Hospitalization - statistics & numerical data; Human Toxicology; Humans; liver failure; liver transplantation; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Male; Medical sciences; Multiple Organ Failure - chemically induced; Multiple Organ Failure - mortality; Other diseases. Semiology; Pharmacology. Drug treatments; Prognosis; Retrospective Studies; Time Factors; United Kingdom; drug-induced liver injury; Digestive system; Toxicity; Acute; Antimigrainous agent; Liver; Overdosing; Hepatic disease; Liver failure; Paracetamol; Analgesic; Antipyretic; Digestive diseases; Complication; Hospital; Hepatic encephalopathy; Liver transplantation