Autologous osteoblasts enhance osseointegration of porous titanium implants

• Published in: Journal of orthopaedic research Vol. 21; no. 2; pp. 213 - 223
• Main Authors: Frosch, K.-H, Sondergeld, I, Dresing, K, Rudy, T, Lohmann, C.H, Rabba, J, Schild, D, Breme, J, Stuermer, K.M
• Format: Journal Article
• Language: English
• Published: Hoboken Elsevier Ltd 01.03.2003; Wiley Subscription Services, Inc., A Wiley Company; Blackwell Publishing Ltd
• Subjects: Animals; Autologous osteoblasts; Cells, Cultured; Coated Materials, Biocompatible; Femur - surgery; Hip Prosthesis; Microscopy, Atomic Force; Microscopy, Confocal; Osseointegration; Osseointegration - physiology; Osteoblasts - physiology; Osteoblasts - transplantation; Rabbits; Surface Properties; Tissue engineering; Tissue Engineering - methods; Titanium; Titanium implants; Transplantation, Autologous; Osseointegration; Autologous osteoblasts; Tissue engineering; Titanium implants

The goal of this study was to assess the osseointegration of porous titanium implants by means of coating with autologous osteoblasts. Titanium implants (8×5×4 mm) having drill channels with diameters of 400, 500, and 600 μm were coated with autologous osteoblasts obtained from spongiosa chips. The...