Long term safety and tolerability of Tafluprost 0.0015% vs Timolol 0.1% preservative-free in ocular hypertensive and in primary open-angle glaucoma patients: a cross sectional study

• Published in: BMC ophthalmology Vol. 17; no. 1; pp. 136 - 8
• Main Authors: Rolle, Teresa, Spinetta, Roberta, Nuzzi, Raffaele
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 03.08.2017; BioMed Central; BMC
• Subjects: Aged; Antihypertensive Agents - administration & dosage; Beta blockers; Cataracts; Comparative analysis; Confocal microscopy; Cornea; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug therapy; Drug Tolerance; Epithelial cells; Eye surgery; Female; Follow-Up Studies; Glaucoma; Glaucoma, Open-Angle - drug therapy; Glaucoma, Open-Angle - physiopathology; Health aspects; Humans; Hypertension; In vivo confocal microscopy; Intraocular pressure; Intraocular Pressure - drug effects; Kruskal-Wallis test; Lasers; Male; Microscopy; Microscopy, Confocal; Middle Aged; Nerves; Ocular Hypertension - drug therapy; Ocular Hypertension - physiopathology; Ocular surface; Open-angle glaucoma; Ophthalmic Solutions; Ophthalmology; Preservatives; Preservatives, Pharmaceutical; Primary open angle glaucoma; Prostaglandins F - administration & dosage; Questionnaires; Side effects; Tafluprost; Tears - chemistry; Time Factors; Timolol; Timolol - administration & dosage; Timolol maleate; Timolol preservative free; Tonometry, Ocular; Trauma; Treatment Outcome; Tafluprost; Ocular surface; In vivo confocal microscopy; Primary open angle glaucoma; Timolol preservative free

The effects of preservatives of antiglaucoma medications on corneal surface and tear function have been widely shown in literature; it's not the same as regards the active compounds themselves. The purpose of our study was to compare Ocular Surface Disease (OSD) signs and symptoms of Tafluprost...