Novel lncRNA-IUR suppresses Bcr-Abl-induced tumorigenesis through regulation of STAT5-CD71 pathway - Wang, Xuefei; Yang, Jianling; Guo, Guijie; Feng, Riyue; Chen, Ke; Liao, Yuan; Zhang, Lianfeng; Sun, Liping; Huang, Shile; Chen, Ji-Long (Molecular cancer, 2019)
Keywords: Acute lymphoblastic leukemia; Acute lymphocytic leukemia; Adolescent; Adult; Animals; Antigens, CD - genetics; Antigens, CD - metabolism; Antineoplastic agents; Antineoplastic Agents - pharmacology; Apoptosis; Bcr-Abl; BCR-ABL protein; Bone marrow; Bone marrow transplantation; Bosutinib; Cancer; Carcinogenesis - genetics; Carcinogenesis - metabolism; Carcinogenesis - pathology; Cell cycle; Cell Line, Tumor; Cell survival; Cellular transformation; Child, Preschool; Chromosome 9; Dasatinib; DNA microarrays; Female; Fusion protein; Fusion Proteins, bcr-abl - genetics; Fusion Proteins, bcr-abl - metabolism; Gene expression; Gene Expression Regulation, Neoplastic; Genetic aspects; Genetic engineering; Genetic transformation; Genomes; Humans; Imatinib; Imatinib Mesylate - pharmacology; Immunoprecipitation; Kinases; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy; Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism; Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology; Leukemogenesis; LncRNA; Lymphatic leukemia; Lymphocytes; Lymphocytic leukemia; Male; Mice; Mice, Nude; Nilotinib; Novels; Oligoribonucleotides - genetics; Oligoribonucleotides - metabolism; Peripheral blood; Ponatinib; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - metabolism; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology; Proteins; Receptors, Transferrin - genetics; Receptors, Transferrin - metabolism; Ribonucleic acid; RNA; RNA, Long Noncoding - agonists; RNA, Long Noncoding - antagonists & inhibitors; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; RNA, Small Interfering - genetics; RNA, Small Interfering - metabolism; Signal Transduction; Stat5 protein; STAT5 Transcription Factor - genetics; STAT5 Transcription Factor - metabolism; Systematic review; Targeted cancer therapy; Transformed cells; Transgenic animals; Transgenic mice; Tumor suppressor genes; Tumorigenesis; Tumors; Xenograft Model Antitumor Assays; Xenografts; Beijing China; United States--US; China; LncRNA; Bcr-Abl; Imatinib; Cellular transformation; Leukemia