Blast traumatic brain injury and serum inflammatory cytokines: a repeated measures case-control study among U.S. military service members

• Published in: Journal of neuroinflammation Vol. 17; no. 1; pp. 20 - 12
• Main Authors: Rusiecki, Jennifer, Levin, Lynn I., Wang, Li, Byrne, Celia, Krishnamurthy, Jayasree, Chen, Ligong, Galdzicki, Zygmunt, French, Louis M.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.01.2020; BioMed Central; BMC
• Subjects: Armed forces; Brain; Codes; Cytokines; Genetic aspects; Head injuries; Health aspects; Immune response; Inflammation; Injuries; Interleukin 1; Interleukin 4; Interleukin 6; Interleukin 8; Melanoma; Metalloproteinase; Military personnel; Military service; Operation enduring freedom; Operation Iraqi freedom; Schizophrenia; Serum levels; Skin cancer; Studies; TBI; Trauma; Traumatic brain injury; Tumor necrosis factor-TNF; Tumors; Within-subjects design; United States; United States > US; Traumatic brain injury; Cytokines; Operation enduring freedom; Operation Iraqi freedom; Inflammation; TBI; Microarray; Protein; Military

There is a paucity of human data on exposure to blast traumatic brain injury (bTBI) and the corresponding systemic cytokine immune response at later time points (i.e., months, years) post-injury. We conducted a repeated measures, case-control study, examining associations of serum levels of pro- and...