Image-Derived Input Function Derived from a Supervised Clustering Algorithm: Methodology and Validation in a Clinical Protocol Using [11C](R)-Rolipram - Lyoo, Chul Hyoung; Zanotti-Fregonara, Paolo; Zoghbi, Sami S.; Liow, Jeih-San; Xu, Rong; Pike, Victor W.; Zarate, Carlos A.; Fujita, Masahiro; Innis, Robert B. (PloS one, 2014)
Keywords: Adult; Algorithms; Arteries; Automation; Biology; Brain; Brain research; Carbon Radioisotopes; Carotid arteries; Carotid Arteries - diagnostic imaging; Carotid Arteries - physiopathology; Carotid artery; Case-Control Studies; Cluster Analysis; Clustering; Clusters; Computer Science; Depressive Disorder, Major - blood; Depressive Disorder, Major - diagnostic imaging; Depressive Disorder, Major - metabolism; Depressive Disorder, Major - physiopathology; Female; Humans; Image processing; Image Processing, Computer-Assisted - methods; Kinetics; Magnetic resonance; Magnetic resonance imaging; Male; Mathematics; Medical imaging; Medicine; Mental depression; Mental health; Metabolites; Methods; Neuroimaging; Plasma; Positron emission; Positron emission tomography; Radioactive tracers; Rolipram; Rolipram - metabolism; Studies; Tomography; Variability; Veins & arteries; United States--US; Maryland