Crosstalk between tumor cells and lymphocytes modulates heparanase expression - Theodoro, Thérèse Rachell; Matos, Leandro Luongo; Cavalheiro, Renan Pelluzzi; Justo, Giselle Zenker; Nader, Helena Bonciani; Pinhal, Maria Aparecida Silva (Journal of translational medicine, 2019)
Keywords: Angiogenesis; Antibodies; Biosynthesis; Bone marrow; Breast cancer; Breast neoplasms; Breast Neoplasms - genetics; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; Cancer cells; Cancer metastasis; Cancer therapies; Cell adhesion & migration; Cell Communication - drug effects; Cell Communication - physiology; Cell culture; Cell growth; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned - pharmacology; Exosomes; Extracellular matrix; Female; Gene expression; Gene Expression Regulation, Enzymologic - drug effects; Gene Expression Regulation, Neoplastic - drug effects; Glucuronidase - genetics; Glucuronidase - metabolism; Growth factors; Health aspects; Heparan sulfate; Heparitin Sulfate - metabolism; Heparitin Sulfate - physiology; HPSE; HPSE2; Humans; Immunocytochemistry; Lymphocyte Activation - genetics; Lymphocytes; Lymphocytes - metabolism; Lymphocytes - physiology; MCF-7 Cells; Messenger RNA; Metastases; Metastasis; Oligosaccharides; Polymerase chain reaction; Proteoglycans; Receptor Cross-Talk - drug effects; Receptor Cross-Talk - immunology; Risk factors; RNA; Stem cells; Sulfates; Tumor cells; Tumor microenvironment; Tumors; Women's health; California; Heparan sulfate; Breast neoplasms; Proteoglycans; HPSE; HPSE2; Tumor microenvironment