The white matter query language: a novel approach for describing human white matter anatomy

• Published in: Brain Structure and Function Vol. 221; no. 9; pp. 4705 - 4721
• Main Authors: Wassermann, Demian, Makris, Nikos, Rathi, Yogesh, Shenton, Martha, Kikinis, Ron, Kubicki, Marek, Westin, Carl-Fredrik
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2016; Springer Nature B.V; Springer Verlag
• Subjects: Adult; Algorithms; Anatomy & physiology; Atlases as Topic; Biomedical and Life Sciences; Biomedicine; Brain; Brain - anatomy & histology; Brain - pathology; Cell Biology; Cognitive science; Computer Science; Databases, Factual; Diffusion Magnetic Resonance Imaging; Female; Human health and pathology; Humans; Image Processing, Computer-Assisted - methods; Information Storage and Retrieval - methods; Life Sciences; Male; Medical Imaging; Methods Paper; Natural Language Processing; Neural Pathways - anatomy & histology; Neurology; Neuroscience; Neurosciences; NMR; Nuclear magnetic resonance; Reproducibility of Results; Schizophrenia - pathology; Software; Tissues and Organs; User-Computer Interface; White Matter - anatomy & histology; White Matter - pathology; Diffusion MRI; White matter fascicles; Computational neuroanatomy; Automatic classification of white matter tracts; Tractography; diffusion MRI; white matter; tractography; neuroanatomy

We have developed a novel method to describe human white matter anatomy using an approach that is both intuitive and simple to use, and which automatically extracts white matter tracts from diffusion MRI volumes. Further, our method simplifies the quantification and statistical analysis of white mat...