The Treatment of Rhodiola Mimics Exercise to Resist High-Fat Diet-Induced Muscle Dysfunction via Sirtuin1-Dependent Mechanisms

• Published in: Frontiers in Pharmacology Vol. 12; p. 646489
• Main Authors: You, Baiyang, Dun, Yaoshan, Fu, Siqian, Qi, Dake, Zhang, Wenliang, Liu, Yuan, Qiu, Ling, Xie, Murong, Liu, Suixin
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media SA 15.04.2021; Frontiers Media S.A
• Subjects: atrogenes; mitochondrion; Pharmacology; rhodiola; RM1-950; salidroside; SIRT1; Therapeutics. Pharmacology; salidroside; rhodiola; SIRT1; atrogenes; mitochondrion

Muscle dysfunction is a complication of high-fat diet (HFD)-induced obesity that could be prevented by exercise, but patients did not get enough therapeutic efficacy from exercise due to multiple reasons. To explore alternative or supplementary approaches to prevent or treat muscle dysfunction in in...