Revisiting the complete blood count and clinical findings at diagnosis of childhood acute lymphoblastic leukemia: 10-year experience at a single center
Heterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete blood count abnormalities and its combinations, symptoms and physical findings were investigated in Hispanic children from an open population at the diagnosis of ac...
Saved in:
| Published in | Hematology, Transfusion and Cell Therapy Vol. 41; no. 1; pp. 57 - 61 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English Portuguese |
| Published |
Brazil
Elsevier Editora Ltda
01.01.2019
Sociedade Brasileira de Hematologia e Hemoterapia Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular (ABHH) Elsevier |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Heterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete blood count abnormalities and its combinations, symptoms and physical findings were investigated in Hispanic children from an open population at the diagnosis of acute lymphoblastic leukemia.
The patient charts and electronic records of under 16-year-old children diagnosed with acute lymphoblastic leukemia over 10 years at a regional hematology center of a university hospital were analyzed to retrieve data concerning the complete blood count at first evaluation. Type and distribution of abnormal data, frequency of symptoms and physical findings at presentation were documented.
The records of 203 children aged 0–15 years diagnosed with acute lymphoblastic leukemia from 2006 to 2016 were revisited. The results of the blood workup showed a median white blood cell count of 7120×109/L (range: 450–600,000×109/L), and a median hemoglobin concentration of 7.5g/dL (range: 2.4–15.3g/dL), whereas the median platelet count was 47,400×109/L (range: 4000–544,000×109/L). Leukocytosis and leukopenia were present in 36.6% and 36.1% of cases, respectively; anemia was diagnosed in 82.9% children. The order of frequency for major clinical symptoms was fatigue 62%, fever 60%, bone and joint pain 39%, hyporexia 33% and weight loss 21%, while main physical findings were hepatomegaly 78%, splenomegaly 63%, lymphadenopathy 57%, pallor 48%, and purpura 30%.
Data differing from those classically expected at diagnosis of acute lymphoblastic leukemia in children were documented in a cohort of Hispanic children over one decade with a wide spectrum of complete blood count abnormalities, forms of presentation and frequency of physical findings. |
|---|---|
| AbstractList | Background: Heterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete blood count abnormalities and its combinations, symptoms and physical findings were investigated in Hispanic children from an open population at the diagnosis of acute lymphoblastic leukemia. Methods: The patient charts and electronic records of under 16-year-old children diagnosed with acute lymphoblastic leukemia over 10 years at a regional hematology center of a university hospital were analyzed to retrieve data concerning the complete blood count at first evaluation. Type and distribution of abnormal data, frequency of symptoms and physical findings at presentation were documented. Results: The records of 203 children aged 0–15 years diagnosed with acute lymphoblastic leukemia from 2006 to 2016 were revisited. The results of the blood workup showed a median white blood cell count of 7120 × 109/L (range: 450–600,000 × 109/L), and a median hemoglobin concentration of 7.5 g/dL (range: 2.4–15.3 g/dL), whereas the median platelet count was 47,400 × 109/L (range: 4000–544,000 × 109/L). Leukocytosis and leukopenia were present in 36.6% and 36.1% of cases, respectively; anemia was diagnosed in 82.9% children. The order of frequency for major clinical symptoms was fatigue 62%, fever 60%, bone and joint pain 39%, hyporexia 33% and weight loss 21%, while main physical findings were hepatomegaly 78%, splenomegaly 63%, lymphadenopathy 57%, pallor 48%, and purpura 30%. Conclusion: Data differing from those classically expected at diagnosis of acute lymphoblastic leukemia in children were documented in a cohort of Hispanic children over one decade with a wide spectrum of complete blood count abnormalities, forms of presentation and frequency of physical findings. Keywords: Acute lymphoblastic leukemia, Complete blood count, Leukocytosis, Hepatomegaly, Splenomegaly Abstract Background Heterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete blood count abnormalities and its combinations, symptoms and physical findings were investigated in Hispanic children from an open population at the diagnosis of acute lymphoblastic leukemia. Methods The patient charts and electronic records of under 16-year-old children diagnosed with acute lymphoblastic leukemia over 10 years at a regional hematology center of a university hospital were analyzed to retrieve data concerning the complete blood count at first evaluation. Type and distribution of abnormal data, frequency of symptoms and physical findings at presentation were documented. Results The records of 203 children aged 0-15 years diagnosed with acute lymphoblastic leukemia from 2006 to 2016 were revisited. The results of the blood workup showed a median white blood cell count of 7120 × 109/L (range: 450-600,000 × 109/L), and a median hemoglobin concentration of 7.5 g/dL (range: 2.4-15.3 g/dL), whereas the median platelet count was 47,400 × 109/L (range: 4000-544,000 × 109/L). Leukocytosis and leukopenia were present in 36.6% and 36.1% of cases, respectively; anemia was diagnosed in 82.9% children. The order of frequency for major clinical symptoms was fatigue 62%, fever 60%, bone and joint pain 39%, hyporexia 33% and weight loss 21%, while main physical findings were hepatomegaly 78%, splenomegaly 63%, lymphadenopathy 57%, pallor 48%, and purpura 30%. Conclusion Data differing from those classically expected at diagnosis of acute lymphoblastic leukemia in children were documented in a cohort of Hispanic children over one decade with a wide spectrum of complete blood count abnormalities, forms of presentation and frequency of physical findings. BACKGROUNDHeterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete blood count abnormalities and its combinations, symptoms and physical findings were investigated in Hispanic children from an open population at the diagnosis of acute lymphoblastic leukemia. METHODSThe patient charts and electronic records of under 16-year-old children diagnosed with acute lymphoblastic leukemia over 10 years at a regional hematology center of a university hospital were analyzed to retrieve data concerning the complete blood count at first evaluation. Type and distribution of abnormal data, frequency of symptoms and physical findings at presentation were documented. RESULTSThe records of 203 children aged 0-15 years diagnosed with acute lymphoblastic leukemia from 2006 to 2016 were revisited. The results of the blood workup showed a median white blood cell count of 7120 × 109/L (range: 450-600,000 × 109/L), and a median hemoglobin concentration of 7.5 g/dL (range: 2.4-15.3 g/dL), whereas the median platelet count was 47,400 × 109/L (range: 4000-544,000 × 109/L). Leukocytosis and leukopenia were present in 36.6% and 36.1% of cases, respectively; anemia was diagnosed in 82.9% children. The order of frequency for major clinical symptoms was fatigue 62%, fever 60%, bone and joint pain 39%, hyporexia 33% and weight loss 21%, while main physical findings were hepatomegaly 78%, splenomegaly 63%, lymphadenopathy 57%, pallor 48%, and purpura 30%. CONCLUSIONData differing from those classically expected at diagnosis of acute lymphoblastic leukemia in children were documented in a cohort of Hispanic children over one decade with a wide spectrum of complete blood count abnormalities, forms of presentation and frequency of physical findings. Heterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete blood count abnormalities and its combinations, symptoms and physical findings were investigated in Hispanic children from an open population at the diagnosis of acute lymphoblastic leukemia. The patient charts and electronic records of under 16-year-old children diagnosed with acute lymphoblastic leukemia over 10 years at a regional hematology center of a university hospital were analyzed to retrieve data concerning the complete blood count at first evaluation. Type and distribution of abnormal data, frequency of symptoms and physical findings at presentation were documented. The records of 203 children aged 0–15 years diagnosed with acute lymphoblastic leukemia from 2006 to 2016 were revisited. The results of the blood workup showed a median white blood cell count of 7120×109/L (range: 450–600,000×109/L), and a median hemoglobin concentration of 7.5g/dL (range: 2.4–15.3g/dL), whereas the median platelet count was 47,400×109/L (range: 4000–544,000×109/L). Leukocytosis and leukopenia were present in 36.6% and 36.1% of cases, respectively; anemia was diagnosed in 82.9% children. The order of frequency for major clinical symptoms was fatigue 62%, fever 60%, bone and joint pain 39%, hyporexia 33% and weight loss 21%, while main physical findings were hepatomegaly 78%, splenomegaly 63%, lymphadenopathy 57%, pallor 48%, and purpura 30%. Data differing from those classically expected at diagnosis of acute lymphoblastic leukemia in children were documented in a cohort of Hispanic children over one decade with a wide spectrum of complete blood count abnormalities, forms of presentation and frequency of physical findings. Heterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete blood count abnormalities and its combinations, symptoms and physical findings were investigated in Hispanic children from an open population at the diagnosis of acute lymphoblastic leukemia. The patient charts and electronic records of under 16-year-old children diagnosed with acute lymphoblastic leukemia over 10 years at a regional hematology center of a university hospital were analyzed to retrieve data concerning the complete blood count at first evaluation. Type and distribution of abnormal data, frequency of symptoms and physical findings at presentation were documented. The records of 203 children aged 0-15 years diagnosed with acute lymphoblastic leukemia from 2006 to 2016 were revisited. The results of the blood workup showed a median white blood cell count of 7120 × 10 /L (range: 450-600,000 × 10 /L), and a median hemoglobin concentration of 7.5 g/dL (range: 2.4-15.3 g/dL), whereas the median platelet count was 47,400 × 10 /L (range: 4000-544,000 × 10 /L). Leukocytosis and leukopenia were present in 36.6% and 36.1% of cases, respectively; anemia was diagnosed in 82.9% children. The order of frequency for major clinical symptoms was fatigue 62%, fever 60%, bone and joint pain 39%, hyporexia 33% and weight loss 21%, while main physical findings were hepatomegaly 78%, splenomegaly 63%, lymphadenopathy 57%, pallor 48%, and purpura 30%. Data differing from those classically expected at diagnosis of acute lymphoblastic leukemia in children were documented in a cohort of Hispanic children over one decade with a wide spectrum of complete blood count abnormalities, forms of presentation and frequency of physical findings. |
| Author | Marfil-Rivera, Luis Javier García-Arellano, Gisela Herrera-Garza, José Luis Jaime-Pérez, José Carlos Gómez-Almaguer, David |
| AuthorAffiliation | Facultad de Medicina y Hospital Universitario, Universidad Autónoma de Nuevo León, Monterrey, Mexico |
| AuthorAffiliation_xml | – name: Facultad de Medicina y Hospital Universitario, Universidad Autónoma de Nuevo León, Monterrey, Mexico – name: Universidad Autónoma de Nuevo León |
| Author_xml | – sequence: 1 givenname: José Carlos surname: Jaime-Pérez fullname: Jaime-Pérez, José Carlos email: carjaime@hotmail.com – sequence: 2 givenname: Gisela surname: García-Arellano fullname: García-Arellano, Gisela – sequence: 3 givenname: José Luis surname: Herrera-Garza fullname: Herrera-Garza, José Luis – sequence: 4 givenname: Luis Javier surname: Marfil-Rivera fullname: Marfil-Rivera, Luis Javier – sequence: 5 givenname: David surname: Gómez-Almaguer fullname: Gómez-Almaguer, David |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30793106$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9ks1u1DAUhSNUREvpC7BAXrKZcG0ndoIQUlXxU6kSEj9ry3FuJh489mAnI-ZJeF0cpozohlWc-Jwvxz73aXHmg8eieE6hpEDFq005TmYqGdCmhLoECo-KC1ZzuqK8kWentWzPi6uUbAcc2qbmjD0pzjnIllMQF8Wvz7i3yU7Wr8k0IjFhu3M4IelcCH1-nf1EtM8rZ7012pHB-j6rE9ET6a1e-5BsImEgZrSuHxeXNnMmuMN2N4bO6TRZQxzO33Fr9WtCYXVAHQn-3GG06A0uKE1SprqcAP2E8VnxeNAu4dX987L49v7d15uPq7tPH25vru9WphYwrZquEoNs20Y0kovK0KoSjOkKwAhW0aFBEKLrh3wN1KBsTdfr7GyBgRayMvyyuD1y-6A3ahftVseDCtqqPx9CXCsdc36HqjdD10oGsut4BYLqqhl4XcuKYTegbjKrPLKSseiC2oQ5-hxefVm6UEsXua4WIJcFUMtseHs07OZui_1y8qjdgxQPd7wd1TrsleCSMrYAXt4DYvgxY5rU1iaDzmmPYU6K0aauhQDOspQdpSaGlCIOp99QUMtEqY1aJkotE6WgVjlkNr34N-DJ8nd-suDNUYC5o73FqJaz50p7GzHD-mD_x_8NXgLeeg |
| CitedBy_id | crossref_primary_10_3390_cancers12123671 crossref_primary_10_4081_itjm_2023_1644 crossref_primary_10_4103_ijh_ijh_1_22 crossref_primary_10_1186_s13104_021_05678_6 crossref_primary_10_1016_j_artmed_2024_102883 crossref_primary_10_1371_journal_pone_0242272 crossref_primary_10_3390_children11020176 crossref_primary_10_1016_j_imu_2022_100971 crossref_primary_10_3390_diagnostics10121064 crossref_primary_10_1016_j_genrep_2021_101237 crossref_primary_10_1542_pir_2022_005733 crossref_primary_10_17533_udea_iatreia_50 |
| Cites_doi | 10.1016/j.bjhh.2015.03.009 10.1002/cncr.28531 10.1056/NEJMoa0900386 10.1136/adc.56.9.684 10.1007/s10552-015-0657-6 10.1586/17474086.2015.978281 10.1136/archdischild-2015-309094 10.1016/j.arcmed.2017.01.004 10.1200/JCO.1996.14.1.18 10.1097/MOP.0b013e32831f1f24 10.1002/pbc.21810 10.1016/j.ejca.2014.01.028 10.1007/s12185-011-0824-9 10.1002/pbc.25583 10.1136/archdischild-2014-307751 10.1136/archdischild-2015-308607 10.1097/CCO.0000000000000125 10.1007/s00277-012-1475-5 10.3324/haematol.13156 10.1056/NEJMra1400972 10.3346/jkms.2015.30.4.463 |
| ContentType | Journal Article |
| Copyright | 2018 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular 2018 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. Published by Elsevier Editora Ltda. 2018 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
| Copyright_xml | – notice: 2018 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular – notice: 2018 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. Published by Elsevier Editora Ltda. 2018 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular – notice: This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. |
| DBID | 6I. AAFTH NPM AAYXX CITATION 7X8 5PM GPN DOA |
| DOI | 10.1016/j.htct.2018.05.010 |
| DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access PubMed CrossRef MEDLINE - Academic PubMed Central (Full Participant titles) SciELO DOAJ Directory of Open Access Journals |
| DatabaseTitle | PubMed CrossRef MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic PubMed |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| EISSN | 2531-1387 |
| EndPage | 61 |
| ExternalDocumentID | oai_doaj_org_article_dcfb97207bb34061a48f355742ebfea8 S2531_13792019000100057 10_1016_j_htct_2018_05_010 30793106 S2531137918301068 |
| Genre | Journal Article |
| GroupedDBID | 6I. AAFTH ALMA_UNASSIGNED_HOLDINGS M~E .1- .FO 0SF AACTN AAEDW AALRI AAXUO ABMAC ABXHO ADBBV ADVLN AEXQZ AFRHN AFTJW AITUG AJUYK AKRWK AMRAJ AOIJS APOWU BCNDV EBS EJD FDB GROUPED_DOAJ HYE NCXOZ NPM OK1 PGMZT ROL RPM RSC SSZ Z5R AAYXX CITATION 7X8 5PM GPN |
| ID | FETCH-LOGICAL-c560t-8b46f7998687364c144622a400c6241f8e066bdf3791ce79cbdac569020a674c3 |
| IEDL.DBID | RPM |
| ISSN | 2531-1379 2531-1387 |
| IngestDate | Thu Jul 04 21:12:40 EDT 2024 Wed Sep 25 03:28:27 EDT 2024 Tue Sep 17 21:04:27 EDT 2024 Fri Aug 16 10:21:13 EDT 2024 Fri Aug 23 01:53:50 EDT 2024 Sat Sep 28 08:43:55 EDT 2024 Sat Apr 29 22:51:53 EDT 2023 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Complete blood count Splenomegaly Leukocytosis Acute lymphoblastic leukemia Hepatomegaly |
| Language | English Portuguese |
| License | This is an open access article under the CC BY-NC-ND license. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. http://creativecommons.org/licenses/by-nc-nd/4.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c560t-8b46f7998687364c144622a400c6241f8e066bdf3791ce79cbdac569020a674c3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371227/ |
| PMID | 30793106 |
| PQID | 2185566032 |
| PQPubID | 23479 |
| PageCount | 5 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_dcfb97207bb34061a48f355742ebfea8 scielo_journals_S2531_13792019000100057 pubmedcentral_primary_oai_pubmedcentral_nih_gov_6371227 proquest_miscellaneous_2185566032 crossref_primary_10_1016_j_htct_2018_05_010 pubmed_primary_30793106 elsevier_sciencedirect_doi_10_1016_j_htct_2018_05_010 |
| PublicationCentury | 2000 |
| PublicationDate | 2019-01-01 |
| PublicationDateYYYYMMDD | 2019-01-01 |
| PublicationDate_xml | – month: 01 year: 2019 text: 2019-01-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Brazil |
| PublicationPlace_xml | – name: Brazil |
| PublicationTitle | Hematology, Transfusion and Cell Therapy |
| PublicationTitleAlternate | Hematol Transfus Cell Ther |
| PublicationYear | 2019 |
| Publisher | Elsevier Editora Ltda Sociedade Brasileira de Hematologia e Hemoterapia Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular (ABHH) Elsevier |
| Publisher_xml | – name: Elsevier Editora Ltda – name: Sociedade Brasileira de Hematologia e Hemoterapia – name: Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular (ABHH) – name: Elsevier |
| References | Hunger, Mullighan (bib0135) 2015; 373 Katz, Chia, Schoonen, Kelsh (bib0205) 2015; 26 Whitlock, Gaynon (bib0175) 2009 Abboud, Ghanem, Muwakkit (bib0155) 2014; 26 Luo, Ke, Huang, Guan, Zhang, Zhang (bib0170) 2009; 52 Erdmann, Kaatsch, Zeeb, Roman, Lightfoot, Schüz (bib0210) 2014; 50 Castro-Jiménez Ángel, Rueda-Arenas, Cabrera-Rodríguez (bib0235) 2015; 113 Bathia S. (bib0130) 2003 Ceppi, Cazzaniga, Colombini, Biondi, Conter (bib0185) 2015; 8 Simpkin, Hinchliffe (bib0195) 2006 Hann, Scarffe, Palmer, Evans, Jones (bib0220) 1981; 56 Jaime-Pérez, López-Razo, García-Arellano, Pinzón-Uresti, Jiménez-Castillo, González-Llano (bib0150) 2016; 47 Vrooman, Silverman (bib0180) 2009; 21 Ling, Capsomidis, Patel (bib0230) 2015; 100 Sen, Moppett, Ramanan (bib0245) 2015; 100 Kim, Park, Lee, Chung, Cho, Lee (bib0215) 2015; 30 Liu, Long, Zhang, Li, Tan, Sun (bib0160) 2011; 93 Smith, Arthur, Camitta, Carroll, Crist, Gaynon (bib0165) 1996; 14 Steele, Narendran (bib0190) 2012; 91 Pui, Campana, Pei, Bowman, Sandlund, Kaste (bib0145) 2009; 360 Fadoo, Nisar, Yousuf, Lakhani, Ashraf, Imam (bib0200) 2015; 62 Lustosa de Sousa, de Almeida Ferreira, Cavalcante Félix, de Oliveira Lopes (bib0140) 2015; 37 Brix, Rosthøj, Herlin, Hasle (bib0250) 2015; 100 Teuffel, Stanulla, Cario, Ludwig, Rottgers, Schafer (bib0225) 2008; 93 Lim, Bhatia, Robison, Yang (bib0240) 2014; 120 Erdmann (10.1016/j.htct.2018.05.010_bib0210) 2014; 50 Liu (10.1016/j.htct.2018.05.010_bib0160) 2011; 93 Simpkin (10.1016/j.htct.2018.05.010_bib0195) 2006 Brix (10.1016/j.htct.2018.05.010_bib0250) 2015; 100 Hunger (10.1016/j.htct.2018.05.010_bib0135) 2015; 373 Steele (10.1016/j.htct.2018.05.010_bib0190) 2012; 91 Jaime-Pérez (10.1016/j.htct.2018.05.010_bib0150) 2016; 47 Luo (10.1016/j.htct.2018.05.010_bib0170) 2009; 52 Kim (10.1016/j.htct.2018.05.010_bib0215) 2015; 30 Lim (10.1016/j.htct.2018.05.010_bib0240) 2014; 120 Abboud (10.1016/j.htct.2018.05.010_bib0155) 2014; 26 Sen (10.1016/j.htct.2018.05.010_bib0245) 2015; 100 Katz (10.1016/j.htct.2018.05.010_bib0205) 2015; 26 Hann (10.1016/j.htct.2018.05.010_bib0220) 1981; 56 Lustosa de Sousa (10.1016/j.htct.2018.05.010_bib0140) 2015; 37 Pui (10.1016/j.htct.2018.05.010_bib0145) 2009; 360 Smith (10.1016/j.htct.2018.05.010_bib0165) 1996; 14 Bathia S. (10.1016/j.htct.2018.05.010_bib0130) 2003 Whitlock (10.1016/j.htct.2018.05.010_bib0175) 2009 Ling (10.1016/j.htct.2018.05.010_bib0230) 2015; 100 Teuffel (10.1016/j.htct.2018.05.010_bib0225) 2008; 93 Castro-Jiménez Ángel (10.1016/j.htct.2018.05.010_bib0235) 2015; 113 Vrooman (10.1016/j.htct.2018.05.010_bib0180) 2009; 21 Ceppi (10.1016/j.htct.2018.05.010_bib0185) 2015; 8 Fadoo (10.1016/j.htct.2018.05.010_bib0200) 2015; 62 Teuffel, O; Stanulla, M; Cario, G; Ludwig, WD; Rottgers, S; Schafer, BW 2008; 93 Sen, ES; Moppett, JP; Ramanan, AV 2015; 100 Luo, XQ; Ke, ZY; Huang, LB; Guan, XQ; Zhang, YC; Zhang, XL 2009; 52 Simpkin, PS; Hinchliffe, RF; Arceci, R; Hann, I; Smith, OP; Victor, H 2006 Hunger, SP; Mullighan, CG 2015; 373 Steele, M; Narendran, A 2012; 91 Brix, N; Rosthøj, S; Herlin, T; Hasle, H 2015; 100 Lustosa de Sousa, DW; de Almeida Ferreira, FV; Cavalcante Félix, FH; de Oliveira Lopes, MV 2015; 37 Kim, S; Park, M; Lee, J; Chung, N; Cho, B; Lee, IG 2015; 30 Smith, M; Arthur, D; Camitta, B; Carroll, AJ; Crist, W; Gaynon, P 1996; 14 Pui, C-H; Campana, D; Pei, D; Bowman, WP; Sandlund, JT; Kaste, SC 2009; 360 Hann, IM; Scarffe, JH; Palmer, MK; Evans, DI; Jones, PH 1981; 56 Lim, JY-S; Bhatia, S; Robison, LL; Yang, JJ 2014; 120 Whitlock, JA; Gaynon, PS; Greer, JP; Foerster, J; Rodgers, GM; Paraskevas, F; Glader, B; Arber, DA; Means, RT 2009 Erdmann, F; Kaatsch, P; Zeeb, H; Roman, E; Lightfoot, T; Schüz, J 2014; 50 Katz, AJ; Chia, VM; Schoonen, WM; Kelsh, MA 2015; 26 Abboud, MR; Ghanem, K; Muwakkit, S 2014; 26 Vrooman, LM; Silverman, LB 2009; 21 Bathia S., RL 2003 Jaime-Pérez, JC; López-Razo, ON; García-Arellano, G; Pinzón-Uresti, MA; Jiménez-Castillo, RA; González-Llano, O 2016; 47 Castro-Jiménez Ángel, M; Rueda-Arenas, E; Cabrera-Rodríguez, D 2015; 113 Ceppi, F; Cazzaniga, G; Colombini, A; Biondi, A; Conter, V 2015; 8 Liu, H; Long, J; Zhang, PH; Li, K; Tan, JJ; Sun, B 2011; 93 Ling, RE; Capsomidis, A; Patel, SR 2015; 100 Fadoo, Z; Nisar, I; Yousuf, F; Lakhani, LS; Ashraf, S; Imam, U 2015; 62 |
| References_xml | – volume: 26 start-page: 1627 year: 2015 end-page: 1642 ident: bib0205 article-title: Acute lymphoblastic leukemia: an assessment of international incidence, survival, and disease burden publication-title: Cancer Causes Control contributor: fullname: Kelsh – volume: 93 start-page: 494 year: 2011 end-page: 501 ident: bib0160 article-title: Elevated beta-arrestin1 expression correlated with risk stratification in acute lymphoblastic leukemia publication-title: Int J Hematol contributor: fullname: Sun – volume: 30 start-page: 463 year: 2015 end-page: 469 ident: bib0215 article-title: Neurocognitive outcome in survivors of childhood acute lymphoblastic leukemia: experience at a tertiary care hospital in Korea publication-title: J Korean Med Sci contributor: fullname: Lee – volume: 100 start-page: 1098 year: 2015 end-page: 1099 ident: bib0230 article-title: Urgent suspected cancer referrals for childhood lymphadenopathy publication-title: Arch Dis Child contributor: fullname: Patel – volume: 21 start-page: 1 year: 2009 end-page: 8 ident: bib0180 article-title: Childhood acute lymphoblastic leukemia: update on prognostic factors publication-title: Curr Opin Pediatr contributor: fullname: Silverman – volume: 37 start-page: 223 year: 2015 end-page: 229 ident: bib0140 article-title: Acute lymphoblastic leukemia in children and adolescents: prognostic factors and analysis of survival publication-title: Rev Bras Hematol Hemoter contributor: fullname: de Oliveira Lopes – volume: 56 start-page: 684 year: 1981 end-page: 686 ident: bib0220 article-title: Haemoglobin and prognosis in childhood acute lymphoblastic leukaemia publication-title: Arch Dis Child contributor: fullname: Jones – volume: 360 start-page: 2730 year: 2009 end-page: 2741 ident: bib0145 article-title: Treating childhood acute lymphoblastic leukemia without cranial irradiation publication-title: N Engl J Med contributor: fullname: Kaste – volume: 91 start-page: 1513 year: 2012 end-page: 1518 ident: bib0190 article-title: Mechanisms of defective erythropoiesis and anemia in pediatric acute lymphoblastic leukemia (ALL) publication-title: Ann Hematol contributor: fullname: Narendran – volume: 47 start-page: 668 year: 2016 end-page: 676 ident: bib0150 article-title: Results of treating childhood acute lymphoblastic leukemia in a low-middle income country: 10 year experience in Northeast Mexico publication-title: Arch Med Res contributor: fullname: González-Llano – volume: 120 start-page: 955 year: 2014 end-page: 962 ident: bib0240 article-title: Genomics of racial and ethnic disparities in childhood acute lymphoblastic leukemia publication-title: Cancer contributor: fullname: Yang – volume: 100 start-page: 811 year: 2015 end-page: 812 ident: bib0245 article-title: Are you missing leukaemia? publication-title: Arch Dis Child contributor: fullname: Ramanan – volume: 373 start-page: 1541 year: 2015 end-page: 1552 ident: bib0135 article-title: Acute lymphoblastic leukemia in children publication-title: N Engl J Med contributor: fullname: Mullighan – volume: 62 start-page: 1700 year: 2015 end-page: 1708 ident: bib0200 article-title: Clinical features and induction outcome of childhood acute lymphoblastic leukemia in a lower/middle income population: a multi-institutional report from Pakistan publication-title: Pediatr Blood Cancer contributor: fullname: Imam – start-page: 1081 year: 2003 end-page: 1100 ident: bib0130 article-title: Epidemiology of leukemia in childhood publication-title: Nathan and Oski's hematology of infancy and childhood contributor: fullname: Bathia S. – volume: 26 start-page: 650 year: 2014 end-page: 655 ident: bib0155 article-title: Acute lymphoblastic leukemia in low and middle income countries: disease characteristics and treatment results publication-title: Curr Opin Oncol contributor: fullname: Muwakkit – volume: 52 start-page: 191 year: 2009 end-page: 195 ident: bib0170 article-title: High-risk childhood acute lymphoblastic leukemia in China: factors influencing the treatment and outcome publication-title: Pediatr Blood Cancer contributor: fullname: Zhang – volume: 100 start-page: 821 year: 2015 end-page: 825 ident: bib0250 article-title: Arthritis as presenting manifestation of acute lymphoblastic leukaemia in children publication-title: Arch Dis Child contributor: fullname: Hasle – volume: 8 start-page: 57 year: 2015 end-page: 70 ident: bib0185 article-title: Risk factors for relapse in childhood acute lymphoblastic leukemia: prediction and prevention publication-title: Expert Rev Hematol contributor: fullname: Conter – volume: 14 start-page: 18 year: 1996 end-page: 24 ident: bib0165 article-title: Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia publication-title: J Clin Oncol contributor: fullname: Gaynon – start-page: 792 year: 2006 end-page: 810 ident: bib0195 article-title: Reference values publication-title: Pediatric hematology contributor: fullname: Hinchliffe – volume: 50 start-page: 1345 year: 2014 end-page: 1353 ident: bib0210 article-title: Survival from childhood acute lymphoblastic leukaemia in West Germany: does socio-demographic background matter? publication-title: Eur J Cancer contributor: fullname: Schüz – start-page: 1889 year: 2009 end-page: 1917 ident: bib0175 article-title: Acute lymphoblastic leukemia in children publication-title: Wintrobe's clinical hematology contributor: fullname: Gaynon – volume: 93 start-page: 1652 year: 2008 end-page: 1657 ident: bib0225 article-title: Anemia and survival in childhood acute lymphoblastic leukemia publication-title: Haematologica contributor: fullname: Schafer – volume: 113 start-page: 331 year: 2015 end-page: 336 ident: bib0235 article-title: Approach to prediagnostic clinical semiology, noticed by mothers, of childhood acute lymphoblastic leukemia publication-title: Arch Argent Pediatr contributor: fullname: Cabrera-Rodríguez – volume: 37 start-page: 223 issue: 4 year: 2015 ident: 10.1016/j.htct.2018.05.010_bib0140 article-title: Acute lymphoblastic leukemia in children and adolescents: prognostic factors and analysis of survival publication-title: Rev Bras Hematol Hemoter doi: 10.1016/j.bjhh.2015.03.009 contributor: fullname: Lustosa de Sousa – volume: 120 start-page: 955 issue: 7 year: 2014 ident: 10.1016/j.htct.2018.05.010_bib0240 article-title: Genomics of racial and ethnic disparities in childhood acute lymphoblastic leukemia publication-title: Cancer doi: 10.1002/cncr.28531 contributor: fullname: Lim – volume: 360 start-page: 2730 issue: 26 year: 2009 ident: 10.1016/j.htct.2018.05.010_bib0145 article-title: Treating childhood acute lymphoblastic leukemia without cranial irradiation publication-title: N Engl J Med doi: 10.1056/NEJMoa0900386 contributor: fullname: Pui – volume: 56 start-page: 684 issue: 9 year: 1981 ident: 10.1016/j.htct.2018.05.010_bib0220 article-title: Haemoglobin and prognosis in childhood acute lymphoblastic leukaemia publication-title: Arch Dis Child doi: 10.1136/adc.56.9.684 contributor: fullname: Hann – volume: 26 start-page: 1627 issue: 11 year: 2015 ident: 10.1016/j.htct.2018.05.010_bib0205 article-title: Acute lymphoblastic leukemia: an assessment of international incidence, survival, and disease burden publication-title: Cancer Causes Control doi: 10.1007/s10552-015-0657-6 contributor: fullname: Katz – start-page: 1081 year: 2003 ident: 10.1016/j.htct.2018.05.010_bib0130 article-title: Epidemiology of leukemia in childhood contributor: fullname: Bathia S. – start-page: 1889 year: 2009 ident: 10.1016/j.htct.2018.05.010_bib0175 article-title: Acute lymphoblastic leukemia in children contributor: fullname: Whitlock – volume: 8 start-page: 57 issue: 1 year: 2015 ident: 10.1016/j.htct.2018.05.010_bib0185 article-title: Risk factors for relapse in childhood acute lymphoblastic leukemia: prediction and prevention publication-title: Expert Rev Hematol doi: 10.1586/17474086.2015.978281 contributor: fullname: Ceppi – volume: 100 start-page: 1098 issue: 11 year: 2015 ident: 10.1016/j.htct.2018.05.010_bib0230 article-title: Urgent suspected cancer referrals for childhood lymphadenopathy publication-title: Arch Dis Child doi: 10.1136/archdischild-2015-309094 contributor: fullname: Ling – volume: 47 start-page: 668 issue: 8 year: 2016 ident: 10.1016/j.htct.2018.05.010_bib0150 article-title: Results of treating childhood acute lymphoblastic leukemia in a low-middle income country: 10 year experience in Northeast Mexico publication-title: Arch Med Res doi: 10.1016/j.arcmed.2017.01.004 contributor: fullname: Jaime-Pérez – volume: 14 start-page: 18 issue: 1 year: 1996 ident: 10.1016/j.htct.2018.05.010_bib0165 article-title: Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia publication-title: J Clin Oncol doi: 10.1200/JCO.1996.14.1.18 contributor: fullname: Smith – volume: 21 start-page: 1 issue: 1 year: 2009 ident: 10.1016/j.htct.2018.05.010_bib0180 article-title: Childhood acute lymphoblastic leukemia: update on prognostic factors publication-title: Curr Opin Pediatr doi: 10.1097/MOP.0b013e32831f1f24 contributor: fullname: Vrooman – volume: 52 start-page: 191 issue: 2 year: 2009 ident: 10.1016/j.htct.2018.05.010_bib0170 article-title: High-risk childhood acute lymphoblastic leukemia in China: factors influencing the treatment and outcome publication-title: Pediatr Blood Cancer doi: 10.1002/pbc.21810 contributor: fullname: Luo – volume: 50 start-page: 1345 issue: 7 year: 2014 ident: 10.1016/j.htct.2018.05.010_bib0210 article-title: Survival from childhood acute lymphoblastic leukaemia in West Germany: does socio-demographic background matter? publication-title: Eur J Cancer doi: 10.1016/j.ejca.2014.01.028 contributor: fullname: Erdmann – volume: 93 start-page: 494 issue: 4 year: 2011 ident: 10.1016/j.htct.2018.05.010_bib0160 article-title: Elevated beta-arrestin1 expression correlated with risk stratification in acute lymphoblastic leukemia publication-title: Int J Hematol doi: 10.1007/s12185-011-0824-9 contributor: fullname: Liu – volume: 113 start-page: 331 issue: 4 year: 2015 ident: 10.1016/j.htct.2018.05.010_bib0235 article-title: Approach to prediagnostic clinical semiology, noticed by mothers, of childhood acute lymphoblastic leukemia publication-title: Arch Argent Pediatr contributor: fullname: Castro-Jiménez Ángel – volume: 62 start-page: 1700 issue: 10 year: 2015 ident: 10.1016/j.htct.2018.05.010_bib0200 article-title: Clinical features and induction outcome of childhood acute lymphoblastic leukemia in a lower/middle income population: a multi-institutional report from Pakistan publication-title: Pediatr Blood Cancer doi: 10.1002/pbc.25583 contributor: fullname: Fadoo – volume: 100 start-page: 821 issue: 9 year: 2015 ident: 10.1016/j.htct.2018.05.010_bib0250 article-title: Arthritis as presenting manifestation of acute lymphoblastic leukaemia in children publication-title: Arch Dis Child doi: 10.1136/archdischild-2014-307751 contributor: fullname: Brix – start-page: 792 year: 2006 ident: 10.1016/j.htct.2018.05.010_bib0195 article-title: Reference values contributor: fullname: Simpkin – volume: 100 start-page: 811 issue: 9 year: 2015 ident: 10.1016/j.htct.2018.05.010_bib0245 article-title: Are you missing leukaemia? publication-title: Arch Dis Child doi: 10.1136/archdischild-2015-308607 contributor: fullname: Sen – volume: 26 start-page: 650 issue: 6 year: 2014 ident: 10.1016/j.htct.2018.05.010_bib0155 article-title: Acute lymphoblastic leukemia in low and middle income countries: disease characteristics and treatment results publication-title: Curr Opin Oncol doi: 10.1097/CCO.0000000000000125 contributor: fullname: Abboud – volume: 91 start-page: 1513 issue: 10 year: 2012 ident: 10.1016/j.htct.2018.05.010_bib0190 article-title: Mechanisms of defective erythropoiesis and anemia in pediatric acute lymphoblastic leukemia (ALL) publication-title: Ann Hematol doi: 10.1007/s00277-012-1475-5 contributor: fullname: Steele – volume: 93 start-page: 1652 issue: 11 year: 2008 ident: 10.1016/j.htct.2018.05.010_bib0225 article-title: Anemia and survival in childhood acute lymphoblastic leukemia publication-title: Haematologica doi: 10.3324/haematol.13156 contributor: fullname: Teuffel – volume: 373 start-page: 1541 issue: 16 year: 2015 ident: 10.1016/j.htct.2018.05.010_bib0135 article-title: Acute lymphoblastic leukemia in children publication-title: N Engl J Med doi: 10.1056/NEJMra1400972 contributor: fullname: Hunger – volume: 30 start-page: 463 issue: 4 year: 2015 ident: 10.1016/j.htct.2018.05.010_bib0215 article-title: Neurocognitive outcome in survivors of childhood acute lymphoblastic leukemia: experience at a tertiary care hospital in Korea publication-title: J Korean Med Sci doi: 10.3346/jkms.2015.30.4.463 contributor: fullname: Kim – volume: 93 start-page: 494 issue: 4 year: 2011 end-page: 501 article-title: Elevated beta-arrestin1 expression correlated with risk stratification in acute lymphoblastic leukemia publication-title: Int J Hematol contributor: fullname: Liu, H; Long, J; Zhang, PH; Li, K; Tan, JJ; Sun, B – volume: 100 start-page: 1098 issue: 11 year: 2015 end-page: 1099 article-title: Urgent suspected cancer referrals for childhood lymphadenopathy publication-title: Arch Dis Child contributor: fullname: Ling, RE; Capsomidis, A; Patel, SR – start-page: 1889 year: 2009 end-page: 1917 publication-title: Wintrobe's clinical hematology contributor: fullname: Whitlock, JA; Gaynon, PS; Greer, JP; Foerster, J; Rodgers, GM; Paraskevas, F; Glader, B; Arber, DA; Means, RT – volume: 37 start-page: 223 issue: 4 year: 2015 end-page: 229 article-title: Acute lymphoblastic leukemia in children and adolescents: prognostic factors and analysis of survival publication-title: Rev Bras Hematol Hemoter contributor: fullname: Lustosa de Sousa, DW; de Almeida Ferreira, FV; Cavalcante Félix, FH; de Oliveira Lopes, MV – volume: 21 start-page: 1 issue: 1 year: 2009 end-page: 8 article-title: Childhood acute lymphoblastic leukemia: update on prognostic factors publication-title: Curr Opin Pediatr contributor: fullname: Vrooman, LM; Silverman, LB – volume: 47 start-page: 668 issue: 8 year: 2016 end-page: 676 article-title: Results of treating childhood acute lymphoblastic leukemia in a low-middle income country: 10 year experience in Northeast Mexico publication-title: Arch Med Res contributor: fullname: Jaime-Pérez, JC; López-Razo, ON; García-Arellano, G; Pinzón-Uresti, MA; Jiménez-Castillo, RA; González-Llano, O – start-page: 1081 year: 2003 end-page: 1100 publication-title: Nathan and Oski's hematology of infancy and childhood contributor: fullname: Bathia S., RL – volume: 50 start-page: 1345 issue: 7 year: 2014 end-page: 1353 article-title: Survival from childhood acute lymphoblastic leukaemia in West Germany: does socio-demographic background matter? publication-title: Eur J Cancer contributor: fullname: Erdmann, F; Kaatsch, P; Zeeb, H; Roman, E; Lightfoot, T; Schüz, J – volume: 52 start-page: 191 issue: 2 year: 2009 end-page: 195 article-title: High-risk childhood acute lymphoblastic leukemia in China: factors influencing the treatment and outcome publication-title: Pediatr Blood Cancer contributor: fullname: Luo, XQ; Ke, ZY; Huang, LB; Guan, XQ; Zhang, YC; Zhang, XL – volume: 91 start-page: 1513 issue: 10 year: 2012 end-page: 1518 article-title: Mechanisms of defective erythropoiesis and anemia in pediatric acute lymphoblastic leukemia (ALL) publication-title: Ann Hematol contributor: fullname: Steele, M; Narendran, A – volume: 120 start-page: 955 issue: 7 year: 2014 end-page: 962 article-title: Genomics of racial and ethnic disparities in childhood acute lymphoblastic leukemia publication-title: Cancer contributor: fullname: Lim, JY-S; Bhatia, S; Robison, LL; Yang, JJ – volume: 360 start-page: 2730 issue: 26 year: 2009 end-page: 2741 article-title: Treating childhood acute lymphoblastic leukemia without cranial irradiation publication-title: N Engl J Med contributor: fullname: Pui, C-H; Campana, D; Pei, D; Bowman, WP; Sandlund, JT; Kaste, SC – volume: 8 start-page: 57 issue: 1 year: 2015 end-page: 70 article-title: Risk factors for relapse in childhood acute lymphoblastic leukemia: prediction and prevention publication-title: Expert Rev Hematol contributor: fullname: Ceppi, F; Cazzaniga, G; Colombini, A; Biondi, A; Conter, V – volume: 56 start-page: 684 issue: 9 year: 1981 end-page: 686 article-title: Haemoglobin and prognosis in childhood acute lymphoblastic leukaemia publication-title: Arch Dis Child contributor: fullname: Hann, IM; Scarffe, JH; Palmer, MK; Evans, DI; Jones, PH – start-page: 792 year: 2006 end-page: 810 publication-title: Pediatric hematology contributor: fullname: Simpkin, PS; Hinchliffe, RF; Arceci, R; Hann, I; Smith, OP; Victor, H – volume: 93 start-page: 1652 issue: 11 year: 2008 end-page: 1657 article-title: Anemia and survival in childhood acute lymphoblastic leukemia publication-title: Haematologica contributor: fullname: Teuffel, O; Stanulla, M; Cario, G; Ludwig, WD; Rottgers, S; Schafer, BW – volume: 14 start-page: 18 issue: 1 year: 1996 end-page: 24 article-title: Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia publication-title: J Clin Oncol contributor: fullname: Smith, M; Arthur, D; Camitta, B; Carroll, AJ; Crist, W; Gaynon, P – volume: 30 start-page: 463 issue: 4 year: 2015 end-page: 469 article-title: Neurocognitive outcome in survivors of childhood acute lymphoblastic leukemia: experience at a tertiary care hospital in Korea publication-title: J Korean Med Sci contributor: fullname: Kim, S; Park, M; Lee, J; Chung, N; Cho, B; Lee, IG – volume: 62 start-page: 1700 issue: 10 year: 2015 end-page: 1708 article-title: Clinical features and induction outcome of childhood acute lymphoblastic leukemia in a lower/middle income population: a multi-institutional report from Pakistan publication-title: Pediatr Blood Cancer contributor: fullname: Fadoo, Z; Nisar, I; Yousuf, F; Lakhani, LS; Ashraf, S; Imam, U – volume: 113 start-page: 331 issue: 4 year: 2015 end-page: 336 article-title: Approach to prediagnostic clinical semiology, noticed by mothers, of childhood acute lymphoblastic leukemia publication-title: Arch Argent Pediatr contributor: fullname: Castro-Jiménez Ángel, M; Rueda-Arenas, E; Cabrera-Rodríguez, D – volume: 100 start-page: 811 issue: 9 year: 2015 end-page: 812 article-title: Are you missing leukaemia? publication-title: Arch Dis Child contributor: fullname: Sen, ES; Moppett, JP; Ramanan, AV – volume: 26 start-page: 1627 issue: 11 year: 2015 end-page: 1642 article-title: Acute lymphoblastic leukemia: an assessment of international incidence, survival, and disease burden publication-title: Cancer Causes Control contributor: fullname: Katz, AJ; Chia, VM; Schoonen, WM; Kelsh, MA – volume: 373 start-page: 1541 issue: 16 year: 2015 end-page: 1552 article-title: Acute lymphoblastic leukemia in children publication-title: N Engl J Med contributor: fullname: Hunger, SP; Mullighan, CG – volume: 26 start-page: 650 issue: 6 year: 2014 end-page: 655 article-title: Acute lymphoblastic leukemia in low and middle income countries: disease characteristics and treatment results publication-title: Curr Opin Oncol contributor: fullname: Abboud, MR; Ghanem, K; Muwakkit, S – volume: 100 start-page: 821 issue: 9 year: 2015 end-page: 825 article-title: Arthritis as presenting manifestation of acute lymphoblastic leukaemia in children publication-title: Arch Dis Child contributor: fullname: Brix, N; Rosthøj, S; Herlin, T; Hasle, H |
| SSID | ssib030985322 ssib044738437 ssj0002013794 |
| Score | 2.2148383 |
| Snippet | Heterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete blood count... BACKGROUNDHeterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete blood count... Abstract Background Heterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete... Background: Heterogeneity regarding clinical and laboratory findings at diagnosis of acute lymphoblastic leukemia exists. The frequency of complete blood count... |
| SourceID | doaj scielo pubmedcentral proquest crossref pubmed elsevier |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Publisher |
| StartPage | 57 |
| SubjectTerms | Acute lymphoblastic leukemia Complete blood count Hepatomegaly Leukocytosis MEDICINE, GENERAL & INTERNAL Original Splenomegaly |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV07j9QwELbQiYIGgXiFl4yERIEiEtuJHTpAnE4UFMBJ11ljx-YWliy6zRb3S_i7zNjJstFJ0NBFeTiJ57Pnm2TmM2PPfQyiRySV2vtYqjqa0pmoSt8p8ApcZSCpfX5sT07Vh7Pm7GCpL8oJy_LAueNe9T66TotKOyfJ-YAyEX0kRnTBxQC5zLduDoIpRJKsOnRDf4TplNLSqCSgKRB0ZS11N1XQ5GSv89FTYmVtsoxntfBSScx_4ayuktGrOZXXyYWtD73V8S12c6KZ_E1-vdvsWhjusF-fUik5JTpz5H08pZMjaeYpe52nZSM4DLg1lUvy9Ed7-LrlMPI-J-WttnwTuZ8VkTn4HbawvkRUbBxScbwhX4fd9_BjBa85Tr-XOJZ42CsqU1PA6QvFGp-AFEEv7rLT4_df3p2U08IMpUeCNJbGqTZqDNRao2WrPMWUQgBOB74VZO-ARMb1EXu59kF33vWAV3ZITaHVyst77GjYDOEB4xBiUzmogxIY6uH02VcgIngQtdPBdAV7ORvC_sz6G3ZOTPtmyWyWzGarxqLZCvaWbLU_k7Sz0w5ElJ0QZf-FqII1s6XtREMyvcCmVn-9-bMZFhbHKP14gSFsdluLNKpB2lxJUbD7GSb7R5SkUIhxecH0AkCLd1geGVbnSQe8lboWQhfsRYaanaafrf1MKLeEckFaART4U9Xxw__RPY_YDWo0f4Z6zI7Gi114gsRsdE_TGPwNmWM0hg priority: 102 providerName: Directory of Open Access Journals |
| Title | Revisiting the complete blood count and clinical findings at diagnosis of childhood acute lymphoblastic leukemia: 10-year experience at a single center |
| URI | https://dx.doi.org/10.1016/j.htct.2018.05.010 https://www.ncbi.nlm.nih.gov/pubmed/30793106 https://search.proquest.com/docview/2185566032 https://pubmed.ncbi.nlm.nih.gov/PMC6371227 http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2531-13792019000100057&lng=en&tlng=en https://doaj.org/article/dcfb97207bb34061a48f355742ebfea8 |
| Volume | 41 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3LbtQwFLXawoINAvEKj5GRkFigtIntxAk7GLWqkFoQUGnExrIdu03JJNU8Ft3wG_wu9zrJ0FElFmxG87STuce-x_bxMSFvrHesAiTF0lofi9QXsSm8iG0ptBXaJIUObp-n-fGZ-DTLZjskG_fCBNG-NfV-28z32_oiaCuv5vZg1IkdfDmZ5lymDMbsu2RXcr49ROdJCRnoryedEJIXYsjBl2HlLeUyHJDIAH8xvhg20_S6r4uVRY1lWvSOnnhUHEcXuRQPRbqRu4LF_1YKu01Rbyst72Jia27msKMH5P5APumH_iYfkh3XPiK_v4YN5ih_psAGaRCZA5WmQdNOw2ESVLfwbNhEScM6d3u-pHpFq16qVy9p56kdfZKptmsoobkGrHQGCDpUSBu3_unmtX5PoVO-hhZG3cZnGYvSFOctGrgC9AldPCZnR4ffp8fxcFxDbIE2reLCiNxLGL7lheS5sDjSZExDJ2FzhihwQG9M5eEPT62TpTWVhl-WEBGdS2H5E7LXdq17Rqh2PkuMTp1gMACETrVKNPPaapYa6YoyIu_GQKir3pVDjXK1S4URVBhBlWQKIhiRjxirzTfRUTu80S3O1YArVVlvSskSaQxHkqNF4YGLScGc8U4XEcnGSKuBnPSkA4qq_1n56xEWClouLsfo1nXrpQJylQGZTjiLyNMeJptLHBEXEbkFoK172P4EGktwBx8aR0Te9lBTQ6e0VN8Q8AoBz9BBAKcDcC_y8_-u4wW5hyX1M1Ivyd5qsXavgKOtzCTMbcDjya_DCblzOp19_jEJ7fQPXAs7sQ |
| link.rule.ids | 230,315,733,786,790,870,891,2115,27957,27958,53827,53829 |
| linkProvider | National Library of Medicine |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1db9MwFLXGQIIXPgSMMD6MhMQDSpc4TpzwBhNTgW1CsKG9WbZjb9nSdGrTh-2P8He510nKyiQkeGub1k7qY99z7eNjQl4bZ1kJSAqFMS7ksctDnTsemoIrw5WOcuXdPvez8SH_fJQerZF02AvjRftGV6Omnoya6sRrK88nZmvQiW193dvOEhEzyNlvkJvQX5lYTdKTqIAY9NuVjnOR5LyPwqd-7S1OhD8ikQECQ3zTb6fplF8nrUGVZZx3np54WFyCPnIxHot0JXp5k_-VIHadpF7XWt7C0FZfjWI798iP4fk78crZaNHqkbn8wxryn_-g--Ruz2vp--7yA7Jmm4fk5ze_dx2V1RSIJvX6dWDp1MvlqT-ngqoGXvX7M6lfQm-O51S1tOxUgNWcTh01gwUzVWYBJdQXAMOpBu4PFdLaLs7spFLvKIz3F9B5qV1aOGNRiuKUSA13gBaks0fkcOfjwfY47E-CCA0wsjbMNc-cgMwwy0WScYNJLGMKxh-TMQSYBeakSwctGRsrCqNLBb8soKlVJrhJHpP1ZtrYJ4Qq69JIq9hyBrkljNdlpJhTRrFYC5sXAXk7tLA87ww_5KCEO5UIDYnQkFEqARoB-YAgWH4Tzbr9B9PZsexbRJbG6UKwSGidIH9SPHdA8wRnVjur8oCkA4Rkz3s6PgNFVX-t_NWANwmDAq70qMZOF3MJvC0Fnh4lLCAbHf6WtzhAOSBiBZkrz7B6BWDmjcd7WAXkTYdh2Y93c_kde5LEnsTQnABnGnCb89P_ruMluT0-2NuVu5_2v2ySO1hqN_H1jKy3s4V9DlSw1S98x_8Fk81Zyg |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bb9MwGLVgIMQLFwEjjIuRkHhAaRPHjZO9waAat2kCJk28WLZjb9natGrTh_FH-Lt8n5OUhkk87K2X1E7jY3_ns4-PCXllnGUFICkUxriQxy4LdeZ4aHKuDFc6ypR3-zxI94_4p-PR8cZRX160b3Q5qCbTQVWeem3lfGqGnU5sePh1L01EzCBnnxdueJ3cgD7L8n6inkQ5xKG_znSciyTjbSQ-8-tvcSL8MYkMUBjim3ZLTaP-Oq0NKi3jrPH1xAPjEvSSi_FopI0I5o3-e4HsMlG9rLe8ieFtshnJxnfJz-4ZNAKW88Gq1gPz6x97yCs9pHvkTstv6dvmkvvkmq0ekN_f_B52VFhTIJzU69iBrVMvm6f-vAqqKnjV7tOkfim9OllSVdOiUQOWSzpz1HRWzFSZFZQwuQA4zjTkAFAhndjVuZ2WapfCuH8BnZjatZUzFqUoTo1M4A7QinTxkByNP_zY2w_bEyFCA8ysDjPNUycgQ0wzkaTcYDLLmIJxyKQMgWaBQenCQWvGxorc6ELBL3NobpUKbpJHZKuaVfYxocq6UaRVbDmDHBPG7SJSzCmjWKyFzfKAvOlaWc4b4w_ZKeLOJMJDIjxkNJIAj4C8QyCsr0TTbv_BbHEi21aRhXE6FywSWifIoxTPHNA9wZnVzqosIKMORrLlPw2vgaLK_1b-ssOchMEBV3xUZWerpQT-NgK-HiUsINsNBte32ME5IKKHzt5_6H8DUPMG5C20AvK6wbFsx72l_I69SWJvYmhSgDMOuN35yZXreEFuHb4fyy8fDz7vkNtYaDP_9ZRs1YuVfQaMsNbPfd__A1ecXEo |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Revisiting+the+complete+blood+count+and+clinical+findings+at+diagnosis+of+childhood+acute+lymphoblastic+leukemia%3A+10-year+experience+at+a+single+center&rft.jtitle=Hematology%2C+transfusion+and+cell+therapy&rft.au=Jaime-P%C3%A9rez%2C+Jos%C3%A9+Carlos&rft.au=Garc%C3%ADa-Arellano%2C+Gisela&rft.au=Herrera-Garza%2C+Jos%C3%A9+Luis&rft.au=Marfil-Rivera%2C+Luis+Javier&rft.date=2019-01-01&rft.pub=Sociedade+Brasileira+de+Hematologia+e+Hemoterapia&rft.issn=2531-1379&rft.eissn=2531-1387&rft.volume=41&rft.issue=1&rft.spage=57&rft.epage=61&rft_id=info:doi/10.1016%2Fj.htct.2018.05.010&rft_id=info%3Apmid%2F30793106&rft.externalDBID=PMC6371227 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2531-1379&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2531-1379&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2531-1379&client=summon |