Ovarian transposition before radiotherapy in cervical cancer patients: functional outcome and the adequate dose constraint

• Published in: Radiation oncology (London, England) Vol. 14; no. 1; pp. 100 - 7
• Main Authors: Yin, Lina, Lu, Saiquan, Zhu, Jun, Zhang, Weiling, Ke, Guihao
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 10.06.2019; BioMed Central; BMC
• Subjects: Adult; Cancer; Cancer patients; Care and treatment; Cervical cancer; Cervix; Diagnosis; Estrogens; Female; Follicle-stimulating hormone; Glycoproteins; Gonadotropins; Health aspects; Health risk assessment; Hormone replacement therapy; Hormones; Humans; Hysterectomy; Hysterectomy - methods; Irradiation; Menopause; Middle Aged; Mortality; Organ Sparing Treatments; Organs at Risk - radiation effects; Ovarian function; Ovarian transposition; Ovaries; Ovary - radiation effects; Patient outcomes; Pelvis - radiation effects; Phenols (Class of compounds); Preservation; Prognosis; Radiation; Radiation (Physics); Radiation dosage; Radiation therapy; Radiotherapy; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted - methods; Radiotherapy, Intensity-Modulated - methods; Reproductive status; Retrospective Studies; ROC Curve; Sex hormones; Signs and symptoms; Transposition; Uterine Cervical Neoplasms - radiotherapy; Women's health; Young Adult; Ovarian transposition; Ovarian function; Radiotherapy; Cervical cancer

The data regarding a transposed ovary in intensity-modulated radiotherapy (IMRT) are not sufficient. Here we aim to investigate the adequate dose constraint of ovarian transposition before radiotherapy in cervical cancer patients. This was a retrospective analysis of 118 patients with cervical cance...