GlycA, a novel biomarker of systemic inflammation and cardiovascular disease risk

• Published in: Journal of translational medicine Vol. 15; no. 1; p. 219
• Main Authors: Connelly, Margery A, Otvos, James D, Shalaurova, Irina, Playford, Martin P, Mehta, Nehal N
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 27.10.2017; BioMed Central; BMC
• Subjects: Acetylglucosamine - blood; Biological markers; Biomarkers - blood; C-Reactive Protein - metabolism; Cardiovascular disease; Cardiovascular diseases; Cardiovascular Diseases - blood; Cardiovascular Diseases - mortality; GlycA; Health aspects; Health risk assessment; Health risks; Humans; Identification and classification; Inflammation; Inflammation - blood; Mortality; NMR; Nuclear magnetic resonance; Nuclear magnetic resonance spectroscopy; Review; Risk Factors; Cardiovascular disease; GlycA; Nuclear magnetic resonance spectroscopy; Inflammation

GlycA is a novel spectroscopic marker of systemic inflammation with low intra-individual variability and other attributes favoring its clinical use in patients with chronic inflammatory and autoimmune diseases. GlycA is unique in its composite nature, reflecting both increased glycan complexity and...