Serum albumin to globulin ratio is related to cognitive decline via reflection of homeostasis: a nested case-control study

• Published in: BMC neurology Vol. 16; no. 1; p. 253
• Main Authors: Koyama, Teruhide, Kuriyama, Nagato, Ozaki, Etsuko, Matsui, Daisuke, Watanabe, Isao, Miyatani, Fumitaro, Kondo, Masaki, Tamura, Aiko, Kasai, Takashi, Ohshima, Yoichi, Yoshida, Tomokatsu, Tokuda, Takahiko, Mizuta, Ikuko, Mizuno, Shigeto, Yamada, Kei, Takeda, Kazuo, Matsumoto, Sanae, Nakagawa, Masanori, Mizuno, Toshiki, Watanabe, Yoshiyuki
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 08.12.2016; BioMed Central
• Subjects: Aged; Aging - psychology; Albumin; C-Reactive Protein - metabolism; Case-Control Studies; Cognitive disorders; Cognitive Dysfunction - blood; Development and progression; Female; Globulins; Globulins - metabolism; Homeostasis; Humans; Male; Middle Aged; Neuropsychological Tests; Physiological aspects; Risk Factors; Serum Albumin - metabolism; Japan; Cognitive decline; Mini-mental state examination; Helicobacter pylori; Albumin to globulin ratio; Homeostatic alteration

Recent research suggests that several pathogenetic factors, including aging, genetics, inflammation, dyslipidemia, diabetes, and infectious diseases, influence cognitive decline (CD) risk. However, no definitive candidate causes have been identified. The present study evaluated whether certain serum...