Progress on COVID-19 Chemotherapeutics Discovery and Novel Technology

• Published in: Molecules (Basel, Switzerland) Vol. 27; no. 23; p. 8257
• Main Authors: Zhou, Yalan, Wang, Huizhen, Yang, Li, Wang, Qingzhong
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 26.11.2022; MDPI
• Subjects: Antiviral agents; Antiviral Agents - chemistry; Antiviral Agents - pharmacology; Antiviral Agents - therapeutic use; Antiviral drugs; Bioavailability; Biosynthesis; Chemotherapy; China; Clinical trials; Coronaviruses; COVID-19; COVID-19 vaccines; CRISPR/Cas; Cytokine storm; deep learning; Disease prevention; Disease transmission; Drug development; drug target; Drug therapy; Enzymes; Epidemics; Experiments; Genomes; Humans; Interferon; multiomics analysis; Pandemics; Proteins; Review; SARS-CoV-2; Severe acute respiratory syndrome; Severe acute respiratory syndrome coronavirus 2; Technology; Vaccines; Viral infections; Viruses; China; COVID-19; deep learning; SARS-CoV-2; multiomics analysis; CRISPR/Cas; drug target

COVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel highly contagious and pathogenic coronavirus that emerged in late 2019. SARS-CoV-2 spreads primarily through virus-containing droplets and small particles of air pollution, which greatly...