The effects of highly active antiretroviral therapy on the serum levels of pro-inflammatory and anti-inflammatory cytokines in HIV infected subjects

• Published in: Journal of biomedical science Vol. 25; no. 1; pp. 88 - 8
• Main Authors: Osuji, Faustina Nkechi, Onyenekwe, Charles Chinedu, Ahaneku, Joseph Ebere, Ukibe, Nkiruka Rose
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 03.12.2018; BioMed Central; BMC
• Subjects: Acquired immune deficiency syndrome; Adult; Aged; AIDS; Antiretroviral agents; Antiretroviral drugs; Antiretroviral Therapy, Highly Active - statistics & numerical data; CD4 antigen; Cytokines; Cytokines - blood; Deregulation; Drug therapy; Enzyme-linked immunosorbent assay; Female; Growth factors; HAART; Health aspects; Highly active antiretroviral therapy; HIV; HIV Infections - drug therapy; HIV patients; Homeostasis; Human immunodeficiency virus; Humans; Immune system; Inflammation; Interleukin 10; Interleukin 4; Interleukin 6; Laboratory methods; Lymphocytes; Lymphocytes T; Male; Middle Aged; Patient outcomes; Serum levels; Therapy; Transforming growth factor-b; Tumor necrosis factor-TNF; Tumor necrosis factor-α; Tumors; Viral Load - drug effects; Viruses; Young Adult; γ-Interferon; Cytokines; HIV; HAART

Cytokines play an important role in controlling the homeostasis of the immune system and infection with Human Immunodeficiency virus (HIV) leads to deregulated production of both pro- and anti-inflammatory cytokines. This study was designed to determine the effects of HIV and Highly Active Antiretro...