Excessive immunosuppression by regulatory T cells antagonizes T cell response to schistosome infection in PD-1-deficient mice - Lu, Liaoxun; Li, Tianhan; Feng, Xinyu; Liu, Zhilong; Liu, Yang; Chao, Tianzhu; Gu, Yanrong; Huang, Rong; Zhang, Fanghui; He, Le; Zhou, Binhui; Kong, Eryan; et al. (PLoS pathogens, 2022)
Keywords: Adaptive immunity; Adenosine; Adenosine receptors; Antigens; Biology and Life Sciences; Cancer; CD4 antigen; CD73 antigen; CD8 antigen; Cell division; CRISPR; Eggs; Flatworms; Helper cells; Hepatocytes; Immunoregulation; Immunosuppression; Infections; Infectious diseases; Interleukin 4; Life Sciences; Liver; Lymphocytes; Lymphocytes T; Medicine and Health Sciences; Parasites; Pathogens; Pathology; PD-1 protein; Prevention; Research and Analysis Methods; Rodents; Schistosomiasis; Spleen; Tropical diseases; Viral infections; γ-Interferon