A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial

• Published in: PloS one Vol. 10; no. 9; p. e0138646
• Main Authors: Liu, Yuejun, Cotillard, Aurélie, Vatier, Camille, Bastard, Jean-Philippe, Fellahi, Soraya, Stévant, Marie, Allatif, Omran, Langlois, Clotilde, Bieuvelet, Séverine, Brochot, Amandine, Guilbot, Angèle, Clément, Karine, Rizkalla, Salwa W.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 25.09.2015; Public Library of Science (PLoS)
• Subjects: Adipose tissue; Adult; Aged; Blindness; Blood Glucose - drug effects; Blood Glucose - metabolism; Body Composition - drug effects; Body mass; Body mass index; Body size; Body weight; Carnosine; Carnosine - administration & dosage; Change detection; Chromium; Chromium - administration & dosage; Cinnamomum zeylanicum - chemistry; Cinnamon; Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 2 - prevention & control; Diet; Dietary Supplements; Double-Blind Method; Fasting; Fasting - blood; Fat-free body mass; Female; Glucose; Hemoglobin; Homeostasis; Human health and pathology; Humans; Inflammation; Insulin; Insulin resistance; Life assessment; Life Sciences; Lipids; Male; Markers; Middle Aged; Muscles - anatomy & histology; Muscles - drug effects; Muscles - metabolism; Obesity; Obesity - complications; Obesity - diet therapy; Overweight; Overweight - complications; Overweight - diet therapy; Physical activity; Placebos; Plant Extracts - administration & dosage; Prediabetic State - complications; Prediabetic State - diet therapy; Randomization; Systematic review; France

Preventing or slowing the progression of prediabetes to diabetes is a major therapeutic issue. Our aim was to evaluate the effects of 4-month treatment with a dietary supplement containing cinnamon, chromium and carnosine in moderately obese or overweight pre-diabetic subjects, the primary outcome b...