Cumulative use of therapeutic bladder anticholinergics and the risk of dementia in patients with lower urinary tract symptoms: a nationwide 12-year cohort study

• Published in: BMC geriatrics Vol. 19; no. 1; pp. 380 - 9
• Main Authors: Wang, Yi-Chi, Chen, Yung-Liang, Huang, Chun-Che, Ho, Chung-Han, Huang, Yu-Tung, Wu, Ming-Ping, Ou, Ming-Jung, Yang, Chiu-Hsien, Chen, Ping-Jen
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 30.12.2019; BioMed Central; BMC
• Subjects: Age; Anticholinergics; Bladder; Brain research; Cardiovascular disease; Cohort analysis; Cohort study; Cumulative defined daily doses; Dementia; Dementia disorders; Geriatrics; Health care; Health insurance; Literature reviews; Lower urinary tract symptoms; Medical research; Mental disorders; Older people; Parasympatholytics; Patients; Population studies; Prescription drugs; Retirement benefits; Urinary tract; Urogenital system; Variance analysis; Taiwan; Anticholinergics; Cumulative defined daily doses; Lower urinary tract symptoms; Cohort study; Dementia

Studies have shown an association between lower urinary tract symptoms (LUTS) and an increased risk of dementia. Whether anticholinergic use contributes to the development of dementia in patients with LUTS remains unknown, especially in Asian populations. This study aims to investigate the associati...